Search for dissertations about: "structural markers"
Showing result 21 - 25 of 109 swedish dissertations containing the words structural markers.
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21. Structural and neurohormonal factors in left ventricular hypertrophy and inhibition of the renin-angiotensin-aldosterone system
Abstract : Hypertensive left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. The aim of this thesis was to study how different neurohormonal systems relate to left ventricular mass, and to study structural and functional cardiovascular changes in hypertensive LVH. READ MORE
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22. Cellular markers indicating activation of the hemostatic system : studies on platelets and leukocytes in peripheral human blood
Abstract : Platelet activation is supposed to initiate thrombus formation in many clinical settings such as coronary artery occlusions, stroke, diabetes mellitus complications, and in surgical interventions. Coagulation and thrombosis are also associated with inflammation in septicemia. READ MORE
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23. Arterial Injury due to Infections in Early Life-A Possible Link in Coronary Heart Disease (Functional and Structural Studies in Animals and Children)
Abstract : Although the clinical manifestations of atherosclerotic CHD occur in adult life, the preclinical phase begins long before, seemingly already in childhood. There is supportive evidence from both epidemiological studies and animal experiments that infections could contribute to the pathogenesis of arterial disease, including atherosclerosis. READ MORE
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24. Methods for structural studies of an antibody, screening metabolites in rat urine and analysis of spent cell cultivation media using LC/ESI-MS and chemometrics
Abstract : This thesis describes bioanalytical methods for generating fingerprints of biological systems for extracting relevant information with (protein) drugs in focus. Similarities and differences between samples can reveal the hidden relevant information, which can be used to optimize the production and facilitate the quality control of such protein drugs during their development and manufacture. READ MORE
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25. Resolving the Genomic Complexity of Pediatric Acute Lymphoblastic Leukemia
Abstract : Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer in the Nordic countries. Structural chromosomal rearrangements are a hallmark of ALL and represent key markers for diagnosis, risk stratification and prognosis. READ MORE