Search for dissertations about: "structure function relationships."

Showing result 1 - 5 of 114 swedish dissertations containing the words structure function relationships..

2. 1. Structure-function relationships of hormone-sensitive lipase

   Author : Torben Österlund; Institutionen för translationell medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; mutagenesis; domain; fold; catalytic triad; lipase; structure; enzymology; Proteiner; enzymologi;

   Abstract : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. READ MORE

4. 2. Structure/function relationships of inorganic phosphate transporters

   Author : Dieter R. Samyn; Bengt Persson; Hanna Sychrová; Linnéuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Inorganic phosphate; transporters; Saccharomyces cerevisiae; Biochemistry; Biokemi; Biokemi; Biochemistry;

   Abstract : Of the many nutrients that make the metabolic clock tick, inorganic phosphate fulfills an essential role in all yeast (and other organisms), being necessary for both structural and metabolic purposes. In order to transport phosphate into the cell interior, Saccharomyces cerevisiae makes use of two systems, comprising high- or low-affinity transporters, which are responsible for the cellular accumulation of inorganic phosphate. READ MORE

5. 3. Structure-function relationships of the human Runx1 transcription factor

   Author : Magnus Wolf-Watz; KTH; []
   Keywords : Runx1; Runt domain; CBFâ; transcription; leukemia; protein structure; protein dynamics;

   Abstract : Runx transcription factors contain a DNA-binding andtransactivating α-subunit and a β-subunit (CBFβ)that serves to increase the DNA binding affinity of theα-subunit. The DNA binding domain of Runx proteins isnamed the Runt homology domain (RD) after its strong sequencehomology to theDrosophilaprotein Runt. READ MORE

6. 4. Conserved structure-function relationships in the mediator complex

   Author : Tomas Linder; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Transcription; Mediator; yeast;

   Abstract : The Mediator complex is an essential multiprotein coregulator of RNA polymerase II (pol II)- dependent transcription in fungi and metazoans. Mediator interacts directly with both pol II and sequence-specific transcriptional regulators and thus acting as a bridge between the two. READ MORE

7. 5. Structure-Function Relationships in RuII Complexes with Unconventional Ligands: Photophysical and Photochemical Studies

   Author : Joachim Wallenstein; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; structure-function relationship; spectral component analysis; photochemistry; RuII complexes; photoreaction; hole-transfer;

   Abstract : The rich photophysics, photochemistry and electrochemistry of RuII complexes have attracted intense research interest in widely disparate fields. A large portion of the studied and applied complexes are derived from the archetypical [Ru(bpy)3]2+ (bpy is 2,2’-bipyridine), which absorbs in the visible region, displays a long lived (~1 μs), emissive metal-to-ligand charge transfer state, and shows reversible electrochemistry in both the ground and excited state. READ MORE