Search for dissertations about: "struktur"

Showing result 16 - 20 of 802 swedish dissertations containing the word struktur.

  2. 16. Ribosomal Stalk Protein L12 : Structure, Function and Application

    Author : Chandra Sekhar Mandava; Suparna Sanyal; Knud Nierhaus; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; protein synthesis; L12 dimer; initiation; elongation; G factors; and His-tag; Molecular biology; Molekylärbiologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Ribosomal stalk proteins are known to play important role in protein synthesis. The ‘stalk’, an extended structure on the large subunit of the ribosome is composed mainly of two to three dimers of L12 and one L10 protein, which forms the base of the stalk. In E. READ MORE

  4. 17. Exploring and predicting DNA template dependent variation in transcription

    Author : Harriet Mellenius; Måns Ehrenberg; Johan Elf; Dan Andersson; Otto Berg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription; accuracy; kinetic proofreading; selection; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : Reliable transmission of information from DNA to proteins is a pre-requisite for all life, where substitution errors in the polypeptide chain may arise from transcription, aminoacylation of tRNAs or translation. The fidelity control mechanisms in transcription have nevertheless received little attention, based on the assumption that the transcriptional error is masked by the translational error. READ MORE

  5. 18. Speed and accuracy in transcription and translation : Modelling of transcript and polypeptide elongation

    Author : Harriet Mellenius; Måns Ehrenberg; Johan Elf; Dan Andersson; Stefan Klumpp; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : .... READ MORE

  6. 19. Ribosomal RNA Modification Enzymes : Structural and functional studies of two methyltransferases for 23S rRNA modification in Escherichia coli

    Author : Avinash S. Punekar; Maria Selmer; Martino Bolognesi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; ribosome biogenesis; ribosome assembly; ribosomal RNA; peptidyltransferase center; domain V; post-transcriptional modification; methyltransferases; S-adenosyl-methionine; RlmM; Cm2498; RlmJ; m6A2030; X-ray crystallography; substrate recognition; substrate specificity; catalytic mechanism; evolution; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry;

    Abstract : Escherichia coli ribosomal RNA (rRNA) is post-transcriptionally modified by site-specific enzymes. The role of most modifications is not known and little is known about how these enzymes recognize their target substrates. READ MORE

  7. 20. In Vitro Kinetics of Ribosomal Incorporation of Unnatural Amino Acids

    Author : Jinfan Wang; Anthony Forster; Jason Chin; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ribosome; protein synthesis; unnatural amino acids; kinetics; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Ribosomal incorporation of unnatural amino acids (AAs) into peptides or proteins has found broad applications in studying translation mechanism, discovering potential therapeutics, and probing protein structure and function. However, such applications are generally limited by the low incorporation efficiencies of the unnatural AAs. READ MORE