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Showing result 1 - 5 of 16 swedish dissertations matching the above criteria.

  2. 1. Computational exploration of cancer genomes

    Author : Joakim Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cancer genomics; Transcriptomics; Driver genes; Copy number changes; Immunogenomics; Cancer of unknown primary; Uveal melanoma;

    Abstract : Cancer evolves due to changes in DNA that give a cell an advantage at the expense of the remaining organism. These alterations range from individual base substitutions to broad losses or duplications of chromosomal material. READ MORE

  4. 2. Improved cancer survival with use of common antihistamines. Epidemiological studies on the use of H1-antihistamines and survival in cancer

    Author : Ildikó Fritz; LUCC: Lunds universitets cancercentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiology; histamine H1 antagonists; histamine antagonists; chemotherapy; immunotherapy;

    Abstract : Cancer often results from chronic inflammation, and anti-inflammatory medications are therefore potential candidates for drug repurposing for cancer therapy. H2-antihistamines such as cimetidine have long been studied for their promise as cancer medications, but H1-antihistamines have thus far not been studied widely for this purpose. READ MORE

  5. 3. The impact of Bcl-3 expression and signaling in cancer

    Author : Karunakar Saamarthy; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cyclin D1; BCL3ANT; Colorectal cancer; Melanoma; Prostate cancer; ID; IL-6; Bcl-3;

    Abstract : Bcl-3 is a proto-oncogene and belongs to the inhibitor of κB (IκB) family and is known to be upregulated in numerous cancers. Bcl-3 can initiate transcription of different genes involved in cell survival and cell growth. READ MORE

  6. 4. Childhood bereavement, stress resilience, and cancer risk : an integrated register-based approach

    Author : Beatrice Kennedy; Katja Fall; Fang Fang; Unnur Valdimarsdottír; Scott Montgomery; Meena Kumari; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alcohol; bereavement; cancer; drug use; epidemiology; health behaviour; psychological resilience; smoking; stress;

    Abstract : Accumulating evidence suggests that psychosocial stress and susceptibility to stressful exposures – stress resilience – influence the risk of various health outcomes, but the potential link with cancer occurrence is unclear. The aims of this thesis were to test if loss of a close relative, a marker of severe psychological stress, and stress resilience measured during late adolescence are associated with cancer risk later in life, as well as to explore potential underlying mechanisms. READ MORE

  7. 5. Aspects of Fluorescence diagnostics and photodynamic therapy of non-melanoma skin cancer

    Author : Carin Sandberg; Göteborgs universitet; []
    Keywords : Fotodynamisk terapi; fluorescence diagnostik; non-melanoma skin cancer; actinic keratosis; aminolaevulinic acid; fluorescence contrast; methylaminolaevulinic acid; microdialysis; pain; photodynamic therapy;

    Abstract : Aspects of fluorescence diagnostics and photodynamic therapy in non-melanoma skin cancer. Carin Sandberg Department of Dermatology and Venereology, Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. READ MORE