Search for dissertations about: "subcellular"

Showing result 1 - 5 of 256 swedish dissertations containing the word subcellular.

  2. 1. Antibody-based subcellular localization of the human proteome

    Author : Marie Skogs; Emma Lundberg; Hans Blom; Cecilia Williams; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Human proteome; Subcellular localization; Organelles; Immunofluorescence; Fixation; Permeabilization; Antibody validation; Bioteknologi; Biotechnology;

    Abstract : This thesis describes the use of antibodies and immunofluorescence for subcellular localization of proteins. The key objective is the creation of an open-source atlas with information on the subcellular location of every human protein. READ MORE

  4. 2. Towards subcellular localization of the human proteome using bioimaging

    Author : Charlotte Stadler; Emma Lundberg; Carolina Wählby; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibody; antibody validation; automated image analysis; automated microscopy; cell line; confocal microscopy; fixation; green fluorescent protein GFP ; immunofluorescence IF ; organelle; protein expression; siRNA; subcellular localization;

    Abstract : Since the publication of the complete sequence of the human genome in 2003 there has been great interest in exploring the functions of the proteins encoded by the genes. To reveal the function of each and every protein, investigation of protein localization at the subcellular level has become a central focus in this research area, since the localization and function of a protein is closely related. READ MORE

  5. 3. Computational modeling of the lamprey CPG : from subcellular to network level

    Author : Mikael Huss; Jeanette Hellgren Kotaleski; Anders Lansner; Ranu Jung; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Computer science; Datalogi;

    Abstract : Due to the staggering complexity of the nervous system, computer modelling is becoming one of the standard tools in the neuroscientist's toolkit. In this thesis, I use computer models on different levels of abstraction to compare hypotheses and seek un- derstanding about pattern-generating circuits (central pattern generators, or CPGs) in the lamprey spinal cord. READ MORE

  6. 4. The subcellular distribution of electrolytes : a methodological study using cryoultramicrotomy and X-ray microanalysis

    Author : Lahja Sevéus; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  7. 5. Membrane Proteins in Human Neutrophils - Identification and Characterization of Lipid Rafts in Subcellular Organelles

    Author : Elisabeth Feuk-Lagerstedt; Göteborgs universitet; []
    Keywords : Human neutrophils; Subcellular organelles; Membrane proteins; Lipid rafts; DRMs;

    Abstract : The human neutrophil is an important effector cell in acute inflammation and in the innate immune response against bacteria and fungi. When immune reactions occur in the tissue in response to antigen challenge, neutrophils are the first cells to enter the site of inflammation. READ MORE