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Showing result 1 - 5 of 93 swedish dissertations matching the above criteria.

  2. 1. Adipose tissue as an active organ : blood flow regulation and tissue-specific glucocorticoid metabolism

    Author : Jonas Andersson; Tommy Olsson; Stefan Söderberg; Sverker Jern; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11β-hydroxysteroid dehydrogenase type 1; adipose tissue; autonomic nervous system; blood flow; cortisol; nitric oxide; weight loss.; medicin; Medicine;

    Abstract : Background: Despite advances in the treatment of atherosclerosis, cardiovascular disease is the leading cause of death worldwide. With the population getting older and more obese, the burden of cardiovascular disease may further increase. READ MORE

  4. 2. Obesity-associated inflammation in adipose tissue

    Author : Malin Alvehus; Tommy Olsson; Agneta Holmäng; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose tissue; inflammation; pro-inflammatory cytokines; serum; obesity; weight loss; menopause;

    Abstract : Background: Excess body fat, particularly in the visceral depot, is linked to increased mortality and morbidity, including the development of diseases such as type 2 diabetes, cardiovascular disease, and cancer. Chronic low-grade inflammation in adipose tissue may be a key mediator of obesity-associated diseases. READ MORE

  5. 3. Adipose tissue gene expression & candidate genes for obesity

    Author : Lovisa Johansson; Diabetes - klinisk obesitasforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin resistance; Obesity; Adipose tissue; Adiponutrin; PNPLA; PPARGC1A; Gene expression; Case-control association study; Microarray; Genotyping; Population-based study;

    Abstract : Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene approaches with focus on the adipose tissue. READ MORE

  6. 4. Material Modelling of Adipose Tissue for Traffic Injury Prevention

    Author : Hosein Naseri; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Finite element human body models; Global sensitivity analysis; Obesity; Adipose tissue; Constitutive modelling; Submarining;

    Abstract : Traffic injury is one of the main reasons for traumatic injuries. Obese occupants are among the vulnerable populations with a higher risk of death and severe injuries. Notably, obesity is associated with a thick layer of subcutaneous adipose (fat) tissue. READ MORE

  7. 5. Prolactin receptor expression and prolactin-mediated effects in adipose tissue

    Author : Charlotte Ling; Göteborgs universitet; []
    Keywords : adipose tissue; prolactin receptor; SOCS; leptin; resistin; lipoprotein lipase;

    Abstract : The aim of this study was to investigate the presence of functional prolactin receptors (PRLRs) in white adipose tissue of mice and humans, and the possible functions mediated via PRLRs. In mouse white adipose tissue, three PRLR mRNA isoforms, L-, S2-, and S3-PRLR, and L-PRLR protein expression were detected. READ MORE