Search for dissertations about: "subcutaneous adipose tissue"

Showing result 16 - 20 of 94 swedish dissertations containing the words subcutaneous adipose tissue.

  2. 16. Adipose tissue inflammation, hepatic fat accumulation and insulin resistance

    Author : Maria Kolak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Insulin resistance is the central feature of a variety of metabolic disorders, such as type 2 diabetes and the metabolic syndrome. The incidence of these disorders, often together with obesity, is currently increasing throughout the world. READ MORE

  4. 17. Effects of surgery on substrate metabolism in human adipose tissue

    Author : Göran Felländer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : trauma; insulin resistance; free fatty acids; lactate; pyruvate; glucose; microdialysis; fat cells; catecholamines; cholecystectomy; anesthesia; 133Xe clearance; adipose tissue blood flow; vasodilation.;

    Abstract : The aim of this study was to characterize the effects of cholecystectomy on substrate metabolism in vivo and blood flow in adipose tissue using microdialysis of the tissue interstitial compartment. One day after surgery, general insulin resistance and glucose intolerance developed, there was no involvement of the glucose metabolism in adipose tissue. READ MORE

  5. 18. The effects of endothelin-1 in human adipose tissue

    Author : Anna Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity is a result of an imbalance between energy intake and energy expenditure ending in an excessive accumulation of body fat. Being overweight or obese increases the risk of death because of obesity related complications, e.g. insulin resistance, type 2 diabetes, cardiovascular diseases and some types of cancer. READ MORE

  6. 19. Effects of immunosuppressive drugs on human adipose tissue metabolism

    Author : Maria J Pereira; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; tacrolimus; rapamycin; glucocorticoids; new onset diabetes after transplantation; adipocytes; insulin signalling; glucose uptake; lipolysis; lipogenesis;

    Abstract : The immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious long-term metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. READ MORE

  7. 20. Inflammation and impaired adipogenesis in human white adipose tissue

    Author : Juan Ramón Acosta; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis aimed to study inflammation and adipogenesis capacity in human subcutaneous white adipose tissue with respect to the development of obesity and associated comorbidities, including insulin resistance. Study I showed that the transcription factor, MAFB, was associated with increased adiposity and involved in regulation of TNFα-mediated inflammatory response, yet did not seem to directly influence adipogenesis or metabolism in human adipocytes. READ MORE