Search for dissertations about: "substrate selectivity"
Showing result 11 - 15 of 103 swedish dissertations containing the words substrate selectivity.
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11. Beta-Glycosidases from Hyperthermophiles as Biocatalysts
Abstract : The thesis concerns glycosyl transfer with use of b-glycosidases, most of them from hyperthermophilic organisms. Both optimisation of the reaction conditions and protein engineering in terms of site-directed mutagenesis were used to improve b-glycosidase-catalysed reactions. READ MORE
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12. Computational modelling of enzyme selectivity
Abstract : Enantioselective reactions are one of the ways to produce pure chiral compounds. Understanding the basis of this selectivity makes it possible to guide enzyme design towards more efficient catalysts. READ MORE
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13. Directed Evolution of Glutathione Transferases Guided by Multivariate Data Analysis
Abstract : Evolution of enzymes with novel functional properties has gained much attention in recent years. Naturally evolved enzymes are adapted to work in living cells under physiological conditions, circumstances that are not always available for industrial processes calling for novel and better catalysts. READ MORE
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14. Computer-Assisted Organic Synthesis. Addition to Carbonyl Carbons and Aromatic Substitution
Abstract : This thesis concerns the computer-assisted modelling of additions to ketones and aromatic substitution, and how this modelling can be used within an existing program for synthesis planning. I include a review of existing computer-assisted organic synthesis (CAOS) programs, and discuss how some of these programs deal with knowledge representation. READ MORE
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15. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes
Abstract : The selective formation of carbon-carbon bonds constitutes a key transformation in organic synthesis with useful applications in pharmaceutical or material industry. A particularly versatile tool for carbon-carbon as well as carbon-heteroatom bond formation is palladium catalysis, which allows for mild and selective routes even towards complex structures. READ MORE