Search for dissertations about: "substrate selectivity"

Showing result 16 - 20 of 103 swedish dissertations containing the words substrate selectivity.

  2. 16. Microfabricated Gas Sensors Based on Hydrothermally Grown 1-D ZnO Nanostructures

    Author : Mingzhi Jiao; Hugo Nguyen; Klas Hjort; Anita Lloyd Spetz; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; gas sensor; zinc oxide; on-chip; hydrothermal growth; nanorods; nanowires; annealing; palladium oxide; photoluminescence; alloy; sensitivity; selectivity; stability;

    Abstract : In this thesis, gas sensors based on on-chip hydrothermally grown 1-D zinc oxide (ZnO) nanostructures are presented, to improve the sensitivity, selectivity, and stability of the gas sensors.Metal-oxide-semiconductor (MOS) gas sensors are well-established tools for the monitoring of air quality indoors and outdoors. READ MORE

  4. 17. Exploring the Propanediol Utilization Pathway in Lactobacillus reuteri

    Author : Lu Chen; Bioteknik; []
    Keywords : Lactobacillus reuteri; propanediol utilization pathway; microcompartment; shell proteins; glycerol; 3-hydroxypropionaldehyde; 3-hydroxypropionic acid; 1; 3-propanediol; glycerol dehydratase; 1; 3-propanediol oxidoreductase; propionaldehyde dehydrogenase; redox balance; substrate selectivity;

    Abstract : Concerns regarding environmental issues have led to increasing efforts for investigating sustainable production routes for the future industry that is based on renewable resources. Among the biobased chemicals, the C3-chemicals 3-hydroxypropionaldehyde (3-HPA), 1,3-propanediol (1,3-PDO) and 3-hydroxypropionic acid (3-HP), have been identified as top candidates for the chemical industry. READ MORE

  5. 18. Directed Evolution of Glutathione Transferases with Altered Substrate Selectivity Profiles : A Laboratory Evolution Study Shedding Light on the Multidimensional Nature of Epistasis

    Author : Wei Zhang; Bengt Mannervik; Bengt-Harald Jonsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; glutathione transferase; azathioprine; directed evolution; semi-rational design; catalytic mechanism; saturation mutagenesis; reduced amino acid alphabets; molecular docking; protein evolution; multivariate data analysis; epistasis; fitness landscape; evolutionary trajectories; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : Directed evolution is generally regarded as a useful approach in protein engineering. By subjecting members of a mutant library to the power of Darwinian evolution, desired protein properties are obtained. Numerous reports have appeared in the literature showing the success of tailoring proteins for various applications by this method. READ MORE

  6. 19. Biochemical Studies on a Plant Epoxide Hydrolase : Discovery of a Proton Entry and Exit Pathway and the Use of In vitro Evolution to Shift Enantioselectivity

    Author : Ann Gurell; Mikael Widersten; Bengt Mannervik; Dick Janssen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; epoxide hydrolase; enantioselectivity; in vitro evolution; proton wire; epoxides; selectivity; CASTing; structure-function; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : The work leading to this thesis has provided additional information and novel knowledge concerning structure-function relationship in the potato epoxide hydrolase. Epoxide hydrolases are enzymes catalyzing the hydrolysis of epoxides to yield the corresponding vicinal diols. READ MORE

  7. 20. Alpha-class Glutathione Transferases from Pig: a Comparative Study

    Author : Natalia Fedulova; Bengt Mannervik; Francoise Raffalli-Mathieu; Mario Lo Bello; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; glutathione transferase; substrate selectivity; steroidogenesis; Sus scrofa; functional comparison; irreproducibility; reproducible assays; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : Glutathione transferases (GSTs, EC 2.5.1.18) possess multiple functions and have potential applications in biotechnology. READ MORE