Search for dissertations about: "subtype transition"

Showing result 1 - 5 of 22 swedish dissertations containing the words subtype transition.

  2. 1. Anorectal malformations – surgical aspects and transition

    Author : Louise Tofft; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anorectal malformations ARM ; wound dehiscence; PSARP; transition; focus groups; fistula; colostogram; voiding cystourethrogram; cystoscopy; endoscopy; postoperative scarring; scar treatment; anorectal malformations ARM ; posterior sagittal anorectoplasty PSARP ; wound dehiscence; transition; focus groups; fistula; colostogram; voiding cystourethrogram; cystoscopy; endoscopy; postoperative scarring; scar treatment;

    Abstract : Background: Anorectal malformations (ARM) occur in 1/5000 live births (1.2–1.6:1 male:female). Associated malformations are common, influencing, together with ARM-subtype complexity, long-term outcome, follow-up and need of transitional care. READ MORE

  4. 2. Intratumoral heterogeneity in glioblastoma: subtype transition and cell-to-cell communication

    Author : Min Guo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glioblastoma; intratumoral heterogeneity; subtype transition; intercellular communication; U-343; SOX2; SFRP2; PROX1; THRAP3; TGFBI; NOTCH1; and ADAMTS1;

    Abstract : Glioblastoma is a most aggressive brain tumor with a median overall survival of less than two years. The current treatment is surgery, chemotherapy, and radiotherapy. However, glioblastoma is difficult to treat and recurs some time after treatment. READ MORE

  5. 3. Molecular Classification of Bladder Cancer

    Author : Gottfrid Sjödahl; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder cancer; Subtype; Classification;

    Abstract : Decisions in the treatment of bladder cancer today are based on clinical and pathological risk variables such as tumor stage and tumor grade. The importance of these conventional risk variables is well documented since more than 10 years, and they are used routinely in the clinics. READ MORE

  6. 4. Single-cell RNA sequencing for subtype discovery in Plasmodium falciparum and mammalian cells

    Author : Mtakai Ngara; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Since the dawn of massively parallel sequencing technologies in mid-2000s their utility in profiling the expression of genes in a genome-wide fashion has matured and progressed from cell populations to individual cells. In particular, single-cell RNA sequencing (scRNA-seq) has impacted numerous domains in life sciences and hold immense promise in biology and medicine. READ MORE

  7. 5. Translational genomics of HIV-1 subtype C in India : molecular phylogeny and drug resistance

    Author : Ujjwal Neogi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis describes the translational genomics of HIV-1subtype C in India from its origin to therapeutic response with the aim to improve our knowledge for better therapeutic and preventive strategies to combat HIV/AIDS. In a systemic approach, we identified the molecular phylogeny of HIV-1 subtypes circulating in India and the time to most recent common ancestors (tMRCA) of predominant HIV-1 subtype C strains. READ MORE