Search for dissertations about: "sulphadoxine"

Found 4 swedish dissertations containing the word sulphadoxine.

  2. 1. Treatment of uncomplicated malaria in Guinea-Bissau

    Author : Paul Erik Kofoed; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chloroquine; sulphadoxine; pyrimethamine; amodiaquine; quinine; artemisinine; malaria; children; Guinea-Bissau; efficacy; effectiveness.;

    Abstract : Treatment of malaria has become increasingly difficult due to high levels of resistance to the cheap and commonly used antimalarials. In Guinea-Bissau, the first line drug is chloroquine (CQ), the second line drug is sulfadoxine-pyrimethamine (S/P), and the third line therapy is quinine (QU). READ MORE

  4. 2. Plasmodium falciparum drug transporter genes in emerging malaria multidrug resistance

    Author : Maria Isabel Mendes Veiga; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Malaria is caused by an intracellular protozoan parasite of the genus Plasmodium. The use of chemotherapy, the foremost tool available for the control of the disease, has been challenged in the last decades by the development and spread of drug resistance among malaria parasites. READ MORE

  5. 3. Aspects of molecular markers in drug resistant malaria

    Author : Irina Tatiana Jovel Quiñonez Dalmau; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : BACKGROUND: There were an estimated 207 million cases of malaria in 2012 of which 91% were due to Plasmodium falciparum. Antimalarial drug resistance constitutes a major problem in the efforts to control malaria. READ MORE

  6. 4. Improved malaria case management in under-fives in the era of Artemisinin-based combination therapy in Tanzania

    Author : Billy Ephraim Ngasala; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Malaria microscopy; case management; efficacy; effectiveness; artemether-lumefantrine; retreatment; lumefantrine concentrations; randomized trial; Tanzania;

    Abstract : Early parasite-based diagnosis of malaria prior to treatment is critical for rational drug use, optimal outcome of febrile illness, patient adherence, prevention of parasite drug resistance, and reduced costs of health services. However, most primary health care (PHC) facilities in sub-Saharan Africa have no laboratory support and malaria diagnosis is based on clinical symptoms and signs, which are nonspecific. READ MORE