Search for dissertations about: "superfamily"

Showing result 1 - 5 of 205 swedish dissertations containing the word superfamily.

  1. 1. Quantum chemical modeling of enzymatic reactions applications to the tautomerase superfamily

    University dissertation from Stockholm : KTH

    Author : Robin Sevastik; KTH.; [2008]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Abstract : In this thesis, quantum chemical methods are used to investigate enzymatic reaction mechanisms. The Density functional theory, in particular the hybrid B3LYP functional, is used to model two enzymes belonging to the tautomerase superfamily; 4-Oxalocrotonate Tautomerase (4-OT) and cis-Chloroacrylic Acid Dehalogenase (cis-CAAD). READ MORE

  2. 2. Gene regulation by different proteins of TGFβ superfamily

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Varun Maturi; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; EMT; Snail1; ZEB1; TGFβ; BMP; Gene regulation;

    Abstract : The present thesis discusses how gene regulation by transforming growth factor β (TGFβ) family cytokines is affected by post-translational modifications of different transcription factors. The thesis also focuses on gene regulation by transcription factors involved in TGFβ signaling. READ MORE

  3. 3. Computational exploration of the medium-chain dehydrogenase/reductase superfamily

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medical Biochemistry and Biophysics

    Author : Linus J. Östberg; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The medium-chain dehydrogenase/reductase (MDR) superfamily is a protein family with more than 170,000 members across all phylogenetic branches. In humans there are 18 representatives. READ MORE

  4. 4. Molecular characterization and evolution of alpha-actinin from protozoa to vertebrates

    University dissertation from Umeå : Kemi

    Author : Ana Virel; Umeå universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; alpha-actinin; evolution; spectrin repeat; intragene duplication; phylogenetic tree; spectrin superfamily; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Abstract : alpha-actinin is a ubiquitous protein found in most eukaryotic organisms. The ability to form dimers allows alpha-actinin to cross-link actin in different structures. In muscle cells alpha-actinin is found at the Z-disk of sarcomeres. READ MORE

  5. 5. Cell signaling by Rho and Miro GTPases Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Åsa Fransson; Uppsala universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ras superfamily; Rho GTPases; cytoskeleton; Miro GTPases; mitochondrial dynamics; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi;

    Abstract : The Ras superfamily of GTPases embraces six major branches of proteins: the Ras, Rab, Ran, Arf, Rho and Miro subfamilies. The majority of GTPases function as binary switches that cycle between active GTP-bound and inactive GDP-bound states. This thesis will focus primarily on the biological functions of the Rho and Miro proteins. READ MORE