Search for dissertations about: "superficial tumors"

Showing result 1 - 5 of 8 swedish dissertations containing the words superficial tumors.

  2. 1. Molecular cytogenetic investigations of chromosomal abnormalities in prostate and urinary bladder cancers

    Author : Yi Pan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : prostate cancer; bladder cancer; FISH; SKY;

    Abstract : Tumorigenesis is suggested to be caused by base pair mutations and chromosomal abnormalities leading to inactivation of tumor suppressor genes an activation of oncogenes. However, still it is not clear for the vast majority of these changes how they contribute to the tumorigenesis of the prostate and bladder cancers. READ MORE

  4. 2. Molecular and therapeutic aspects of breast cancer stem cells

    Author : Ran Ma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breast cancer stem cells (BCSCs) are defined as a minor cellular component in the solid tumor, displaying mammary stem cell properties by expressing embryonic stem cell genes. They are usually undergoing self-. READ MORE

  5. 3. Biomarker Discovery in Cutaneous Malignant Melanoma : A Study Based on Tissue Microarrays and Immunohistochemistry

    Author : Margrét Agnarsdóttir; Fredrik Ponten; Peter Naredi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody-based proteomics; automated analysis; biomarker; immunohistochemistry; malignant melanoma; survival; tissue microarray; Tumour biology; Tumörbiologi; Pathology; Patologi; Molecular medicine; Molekylär medicin; Medical Science; Medicinsk vetenskap; Pathology; Patologi;

    Abstract : The incidence of cutaneous malignant melanoma has increased dramatically in Caucasians the last few decades, an increase that is partly explained by altered sun exposure habits. For the individual patient, with a localized disease, the tumor thickness of the excised lesion is the most important prognostic factor. READ MORE

  6. 4. Cancer Immunotherapy : A Preclinical Study of Urinary Bladder Cancer

    Author : Christina Ninalga; Thomas Tötterman; Magnus Essand; Timothy Ratliff; Uppsala universitet; []
    Keywords : Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Abstract : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. READ MORE

  7. 5. Biological and therapeutic aspects of breast cancer progression

    Author : Karthik Govindasamy Muralidharan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breast cancer is the second leading cause of cancer related death in women worldwide1. Although majority of primary breast cancers are curable with current treatment strategies, treatment outcome of metastatic breast cancer is dismal. READ MORE