Search for dissertations about: "surfactant replacement therapy"
Found 5 swedish dissertations containing the words surfactant replacement therapy.
-
1. A Surface Phase Model of the Alveolar Lining: Ultrastructural Analysis and in vivo Applications
Abstract : In this thesis the relation between lung surfactant structure and functional properties have been studied. Experimental results show that the alveolar surface is formed by a coherent surface phase with a structure equal to tubular myelin. The properties of this phase may explain certain unresolved issues in lung physiology, e.g. READ MORE
-
2. Respiratory distress syndrome aspects of inhaled nitric oxide, surfactant and nasal CPAP
Abstract : Respiratory distress syndrome (RDS) still represents one of the main problems in the treatment of premature infants. Despite the use of surfactant replacement therapy RDS adds to the need for endotracheal intubation and mechanical ventilation (M). READ MORE
-
3. Surfactant treatment in neonatal group B streptococcal pneumonia : experimental and clinical studies
Abstract : Surfactant dysfunction is probably involved in the pathophysiology of neonatal group B streptococcal (GBS) pneumonia. Aim of the present studies was to evaluate efficacy and safety of surfactant replacement therapy for term and preterm neonates with severe respiratory failure due to GBS infection. READ MORE
-
4. Development of novel synthetic lung surfactants for treatment of respiratory distress syndrome
Abstract : Pulmonary surfactant is a complex mixture of lipids and specific proteins found in the alveoli and its main role is to reduce the surface tension of the alveolar air/water interface, thereby preventing lung collapse. Lack of pulmonary surfactant in premature babies results in lethal respiratory distress syndrome (RDS), which is today treated with surfactant replacement therapy, i. READ MORE
-
5. Bronchopulmonary dysplasia from newborn disease to long-term sequelae
Abstract : Bronchopulmonary Dysplasia (BPD) is a complication of premature birth that is associated with increased mortality and morbidity in infancy and impaired lung function and obstructive lung disease from childhood to adulthood. The pathogenesis of BPD is multifactorial, and may involve one or more of the following: a deficiency in surfactant production in the immature lung, chronic inflammatory processes before and after birth, oxidative stress, and trauma due to mechanical ventilation. READ MORE