Search for dissertations about: "surgery for spinal metastases"

Found 4 swedish dissertations containing the words surgery for spinal metastases.

2. 1. Clinical and morphological aspects of metastatic spinal cord compression

   Author : Johan Wänman; Sead Crnalic; Lukas Bobinski; Pawel Grabowski; Pernilla Wikström; Anders Bergh; Elin Thysell; Helena Brisby; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bone metastasis; metastatic spinal cord compression; surgery for spinal metastases; Spinal Instability Neoplastic Score; prostate cancer; Orthopaedics; ortopedi; Orthopaedics; ortopedi;

   Abstract : Background: Metastatic spinal cord compression (MSCC) is a serious complication of cancer leading to demyelination and axonal damage of the spinal cord with a risk of para/tetraplegia. It is most common in patients with known cancer but may also be the initial manifestation of malignancy (IMM). READ MORE

4. 2. Surgical treatment of spinal metastasis

   Author : Christian Carrwik; Yohan Robinson; Nasir Quraishi; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spine surgery; oncology; Orthopaedics; Ortopedi;

   Abstract : The aim of this thesis was to study surgical treatment of spinal metastasis from several points of view, with a focus on predictive tools and survival after surgery. Study I includes 315 patients treated surgically at Uppsala University Hospital 2006-2012 due to spinal metastatic disease. READ MORE

5. 3. Metastatic spinal cord compression in prostate cancer : clinical and morphological studies

   Author : Sead Crnalic; Richard Löfvenberg; Anders Widmark; Anders Bergh; Sten Nilsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; bone metastasis; spinal cord compression; surgical treatment; survival prognosis; early diagnosis; androgen receptor; Orthopaedics; ortopedi; Pathology; patologi; Oncology; onkologi;

   Abstract : Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. READ MORE

6. 4. Molecular heterogeneity of prostate cancer bone metastasis

   Author : Erik Bovinder Ylitalo; Pernilla Wikström; Anders Bergh; Maria Brattsand; Vessela Kristensen; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; CRPC; castration-resistant; androgen receptor; splice variant; abiraterone; cabazitaxel; ABCB1; cholesterol; Mdr1; P-gp; bone metastasis; immune response; metabolism; osteoblast; osteoclast; BMP; methylation;

   Abstract : Castration-resistant prostate cancer (CRPC) develops after androgen deprivation therapy of advanced PC, often with metastatic growth in bone. Patients with metastatic CRPC have very poor prognosis. Growth of CRPC, in most but not all patients, seems to involve androgen receptor (AR) activity, despite castrate levels of serum testosterone. READ MORE