Search for dissertations about: "survivin"
Showing result 1 - 5 of 25 swedish dissertations containing the word survivin.
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1. Structural and Interaction Studies of the Human Protein Survivin
Abstract : Cell division and cell death (apoptosis) are two essential processes to maintain the specific number of cells in all multicellular organisms. In humans, the misregulation of these processes leads to severe diseases, such as cancer, and neurological, inflammatory or autoimmune diseases. READ MORE
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2. The MEN 1 Pancreas : Tumor Development and Haploinsufficiency
Abstract : Multiple Endocrine Neoplasia Type I Syndrome (MEN 1) is a monogenic autosomal dominantly inherited cancer syndrome caused by a heterozygous loss of the MEN1 gene, predisposing for endocrine cell proliferation and tumor formation. MEN 1 carriers classically develop tumors in endocrine organs; the parathyroids, the endocrine pancreas, and the pituitary. READ MORE
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3. Prognostic and Predictive Factors in Bladder Cancer
Abstract : Bladder cancer is a potentially curable malignancy; however in regards to the state of current therapy regimens, a plateau has been reached in both the non-muscle and muscle invasive types. To obtain effective treatment, and consequently a decreased mortality, it has become imperative to test and understand aspects affecting therapy response. READ MORE
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4. Polyamine analogues inhibit neuroblastoma cell growth
Abstract : Abstract Neuroblastoma is a highly malignant neoplasm found in children. Although children with high-risk neuroblastoma respond to chemotherapy, relapses are common and an estimated long-time survival prognosis is approximately 15%. Thus, there is a tremendous need for new chemotherapeutic drugs for the treatment for neuroblastoma. READ MORE
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5. The impact of Survivin, WRAP53β, and Hypoxia on treatment response in Head and Neck Cancer
Abstract : Squamous cell carcinoma (SCC) is the most common histological type of cancer in the head and neck region and arises in the epithelial mucosa of the upper aerodigestive tract. Approximately one and a half million people are living with the diagnosis. READ MORE