Search for dissertations about: "sympatric ethnic groups"
Showing result 1 - 5 of 6 swedish dissertations containing the words sympatric ethnic groups.
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1. Plasmodium falciparum-mediated modulation of innate immune cells: responses and regulation
Abstract : Plasmodium falciparum (P. falciparum) infection modulates the response of innate immune cells. The aim of this work was to study the impact of P. falciparum infection and P. READ MORE
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2. Novel immunization strategies and interethnic differences in response to malaria infection
Abstract : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. READ MORE
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3. Human candidate polymorphisms and malaria susceptibility in sympatric ethnic groups, The Fulani and The Dogon of Mali
Abstract : In malaria endemic regions, resistance to malaria constitutes a critical selective pressureon genetic polymorphisms that regulate immune defense and inflammatory pathways.Differences in malaria susceptibility between sympatric ethnic groups have been described inMali. READ MORE
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4. Single nucleotide polymorphisms related to immune responses in Plasmodium falciparum malaria
Abstract : The current research is directed towards dissection of host genetic factors involved in host immune response and the malaria disease outcome. A possible association between FcγRIIa polymorphism and anti-malarial antibody (A.M.A) responses were investigated in Sudanese patients in relation to clinical outcome of falciparum malaria. READ MORE
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5. Host genetic factors and antibody responses with potential involvement in the susceptibility to malaria
Abstract : The relatively lower susceptibility to malaria seen in the Fulani ethnic group in Africa, as compared to other sympatric ethnic groups, has been related to genetic regulation of the immune responses. This thesis aimed to describe important pathways related to the regulation of antibodies in the immune responses during a malaria infection. READ MORE