Search for dissertations about: "synapsis"

Showing result 1 - 5 of 6 swedish dissertations containing the word synapsis.

  2. 1. Chromosome synapsis and recombination in yeast meiosis

    Author : Hasanuzzaman Bhuiyan; Karin Schmekel; Harry Scherthan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; meiosis; recombination; synapsis; yeast; Molecular biology; Molekylärbiologi;

    Abstract : Meiosis is a cell division process that produces haploid gametes from diploid cells. Several important meiotic events take place during prophase of meiosis I, most important being homologous chromosome pairing, meiotic recombination and formation of the synaptonemal complex (SC). READ MORE

  4. 2. Proteins influencing the integrity of meiotic chromosome dynamics

    Author : Mary-Rose Hoja; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Aneuploidy (trisomy or monosomy) is the leading genetic cause of human pregnancy loss and results from aberrant meiotic chromosome segregation. Accurate segregation of meiotic chromosomes depends on extensive pairing (called synapsis) and recombination between them. READ MORE

  5. 3. Molecular analysis of protein complexes involved in pairing of mammalian chromosomes during meiosis

    Author : Jeanette Pelttari Danielsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : How is the accuracy of chromosomal pairing and segregation processes in dividing meiotic cells assured? This is an important question as premature or erratic segregation of chromosomes can give rise to aneuploidy, which is the leading genetic cause of pregnancy loss in humans. Meiosis is a cell division process that produces genetically unique haploid gametes from diploid cells. READ MORE

  6. 4. Identification of novel BRCA2-binding proteins that are essential for meiotic homologous recombination

    Author : Jingjing Zhang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; meiosis; DSB; cancer; BRCA2; MEILB2; BRME1; HR; RAD51; DMC1; DDR;

    Abstract : Meiotic recombination is a molecular process in which the induction and repair of programmed DNA double-strand breaks (DSBs) creates genetic exchange between homologous chromosomes and thus increases genetic diversity and ensures chromosome segregation. Breast cancer susceptibility gene 2 (BRCA2) is a potent cancer suppressor and is required for DSB repair by homologous recombination (HR) in mitosis. READ MORE

  7. 5. Molecular architecture of meiotic chromosomes

    Author : Ivana Novak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Meiosis; Chromosome architecture; Synaptonemal complex; Cohesin complex;

    Abstract : Faithful chromosome segregation at each cell division is essential as the formation of cells with an abnormal number of chromosomes (aneuploid cells) can result in infertility, developmental defects or cancer. Aneuploidy occurs in approximately 20% of all conceptions, causing infertility and embryo death. READ MORE