Search for dissertations about: "syngeneic islet transplantation"
Found 3 swedish dissertations containing the words syngeneic islet transplantation.
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1. Experimental Studies Aiming to Prevent Type 1 Diabetes Mellitus
Abstract : Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cells and macrophages invade the islets of Langerhans and selectively destroy the insulin producing β-cells, either directly or through the secretion of e.g. cytokines and nitric oxide (NO). This thesis has studied possible strategies to prevent T1DM. READ MORE
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2. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus
Abstract : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. READ MORE
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3. Prevention of type 1 diabetes mellitus in experimental studies
Abstract : The aim of the study was to examine the immune response and different immunoprotective strategies in experimental type 1 diabetes mellitus. The autoimmune destruction of the insulin-producing pancreatic β-cells that leads to type 1 diabetes is complex and incompletely understood. READ MORE