Search for dissertations about: "synovia"

Showing result 1 - 5 of 7 swedish dissertations containing the word synovia.

  2. 1. Studies of transforming growth factor alpha in normal and abnormal growth

    Author : Anna-Lotta Hallbeck; Åke Wasteson; Thomas Walz; Annelie Lindström; Carl-Henric Heldin; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-alpha; HER; EGFR; synovia; synovial sarcoma; RA; synovitis; Medical cell biology; Medicinsk cellbiologi;

    Abstract : Regulation of growth is of fundamental importance for development of the organism and to maintain health. The induction of cell proliferation and matrix production are influenced by several different signaling systems, most importantly by growth factors. READ MORE

  4. 2. Characterization of somatic mutations in nonneoplastic cells

    Author : Karin Broberg; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; osteoarthritis; nonneoplastic; HMGIC; trisomy 7; FISH; Molecular genetics; cytogenetics; Klinisk genetik;

    Abstract : Acquired genetic alterations, of which many are visible on the chromosome level, are believed to be necessary for tumorigenesis, and most tumors display characteristic patterns of recurrent structural and numerical aberrations. However, two of the most frequently occurring chromosome mutations in malignant and benign solid tumors, i.e. READ MORE

  5. 3. The Role of Fc gamma Receptors and Mast Cell Chymase in Autoimmune Arthritis

    Author : Sofia Magnusson; Sandra Kleinau; Jeanette Leusen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fc gamma receptors; rheumatoid arthritis; antibodies; mast cells; mast cell; Immunology; Immunologi; Immunologi; Immunology;

    Abstract : In autoimmune diseases such as rheumatoid arthritis (RA), self-reactive antibodies are present at high levels, which contributes to disease pathogenesis. The antibodies mediate their effect predominantly by binding to Fc gamma receptors (FcγR) on various leukocytes, such as monocytes, macrophages and mast cells, where FcγR ligation leads to cell activation. READ MORE

  6. 4. Resistin is a modulator of inflammation and autoimmunity

    Author : Elisabeth Almer Boström; Göteborgs universitet; []
    Keywords : Resistin; inflammation; autoimmunity; rheumatoid arthritis; Sjögren s syndrome;

    Abstract : Resistin is a protein with proinflammatory properties in man and a regulator of glucose metabolism in mice. Human resistin activates the nuclear factor kappa-B dependent cytokine cascade; however, its full role in inflammation in terms of regulation, expression, and cellular source is not entirely understood. READ MORE

  7. 5. Studies on the role of NGF in arthritis-induced pain transmission using gait and weight bearing as outcome measures

    Author : Kristina Ängeby Möller; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pain is one of the most common reasons for seeking healthcare, with approximately forty percent of those suffering from chronic pain having joint pain. Osteoarthritis is the most common cause of joint pain, but currently there are few treatments available. READ MORE