Search for dissertations about: "synovial fluid analysis in joint disease"

Showing result 1 - 5 of 9 swedish dissertations containing the words synovial fluid analysis in joint disease.

  2. 1. Pain and radiographic changes of the arthritic temporomandibular joint : relation to cytokines in synovial fluid and plasma

    Author : Silvi Nordahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Arthritis; Bone loss; Interleukin- 1 beta; Pain; Plasma; Progression; Radiographic changes; Synovial fluid; Temporomandibular joint; Tumor Necrosis Factor alpha;

    Abstract : In patients with rheumatoid arthritis and other inflammatory joint diseases, radiographic changes of the TMJ are frequently observed. Common symptoms of TMJ involvement are pain at rest and on movement of the jaw. READ MORE

  4. 2. Digital Twins : High Resolution Disease Models for Optimized Diagnosis and Treatment

    Author : Sandra Lilja; Mikael Benson; Huan Zhang; Claudio Altafini; Yvan Saeys; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : To study immune-mediated diseases, which can affect the expression of thousands of genes among many different cell types and organs, is a daunting challenge. However, for effective diagnosis and therapeutic treatment it is relevant to understand the regulatory functions of disease. READ MORE

  5. 3. Biochemical biomarkers at the site of inflammation and in peripheral blood

    Author : Anja Finn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Biochemical biomarkers are small molecular species, naturally varying or experimentally induced, which are measurable in body fluids and which may provide alternative or complementary tools to describe disease processes or to assess responses to pharmacological treatment. The focus of this thesis is inflammatory biomarkers, mediators, chemokines and cytokines that attract immune cells and that regulate the course of the inflammatory process at the site of inflammation. READ MORE

  6. 4. Molecular studies on the autoantibody-mediated bone destruction in rheumatoid arthritis

    Author : Akilan Krishnamurthy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autoantibody-positive rheumatoid arthritis (RA), also called seropositive RA, is characterised by the presence of anti citrullinated proteins antibodies (ACPA) that can be detected in blood several years before disease onset. Joint inflammation, pain and bone destruction are major features of the disease. READ MORE

  7. 5. Understanding juvenile idiopathic arthritis : a multidimensional approach

    Author : Raya Saleh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overarching objective of this doctoral thesis is to enhance the understanding of Juvenile Idiopathic Arthritis (JIA), a complex autoimmune disease affecting children. With the aim of filling the knowledge gaps in JIA, we conducted a comprehensive study on biomarkers with distinct biological implications, including genetic variations, autoantibodies, and plasma and synovial fluid proteins, in individuals with JIA and controls. READ MORE