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Showing result 1 - 5 of 19 swedish dissertations matching the above criteria.

  2. 1. Metabolism of articular cartilage proteoglycans in vitro : effects of synovial membrane products and mechanical pressure

    Author : Agneta Klämfeldt; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Articular cartilage; Proteoglycan metabolism; Synovial membrane products; Mechanical stress; Indom ethacin; Glucocorticoids; Prostaglandins; Osteoarthritis; Rheumatoid arthritis;

    Abstract : The effect of synovial membrane products and mechanical pressure upon the metabolism of articular cartilage proteoglycans has been studied in vitro. The degradation of cartilage proteoglycans was studied in an organ culture system and measured as the release of [35S ] sulphate from prelabelled cartilage. READ MORE

  4. 2. Studies of the synovial membrane in chronic rheumatic joint disease

    Author : Erik af Klint; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The synovial membrane (SM) outlines the inner cavity of synovial joints except for cartilage surfaces. The SM is the target organ of immune-mediated responses in chronic arthritis, including rheumatoid arthritis (RA). RA is a common joint disease (prevalence of 0.5-1. READ MORE

  5. 3. Synovial metabolism after knee joint arthroscopy : a microdialysis study

    Author : Erland Högberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Microdialysis; synovial membrane; knee joint; arthroscopy; trauma;

    Abstract : Postoperative pain and swelling of the knee is a general finding after arthroscopy. In order to optimize and individualize the treatment it is of great importance to increase basic knowledge of perioperative local biochemical events in the synovial membrane. READ MORE

  6. 4. Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis

    Author : Petra Neregård; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability. Despite recent progress in the therapeutic field of RA, the exact molecular mechanisms responsible for chronic joint inflammation are not yet completely understood. READ MORE

  7. 5. Synovial metabolism after different degrees of trauma : effects of pharmacological and physiological intervention : a microdialysis study of the knee joint synovium

    Author : Anders Stålman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Knee arthroscopy is one of the most common orthopedic procedures. Postoperative pain and knee swelling is often a problem. Optimal pain management in knee arthroscopic procedures is important to permit same-day discharge and to contribute to early mobilisation, reduced cost and increased patient satisfaction. READ MORE