Search for dissertations about: "synteny"

Showing result 1 - 5 of 21 swedish dissertations containing the word synteny.

2. 1. Evolution of acetylcholine receptors and study of the anatomy of the mouse brain reward system

   Author : Julia Pedersen; Dan Larhammar; Arnaud Chatonnet; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ventral Tegmental Area; Mesocorticolimbic system; Glutamate; Optogenetics; Histology; Acetylcholine; Receptor; Muscarininc; Nicotinic; G protein-coupled receptor; Gene duplication; Tetraploidization; Synteny; Paralogon; Ohnolog; Zebrafish; Spotted gar; Neuroscience; Neurovetenskap;

   Abstract : This thesis work is divided in two parts. In the first part, I make use of the transgenic TRPV1-Cre mouse line as a tool to investigate the midbrain ventral tegmental area (VTA). READ MORE

4. 2. Quantitative Genetics and Genome Structure in a Wild Population: the Use of a Great Reed Warbler Pedigree

   Author : Mikael Åkesson; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; genome mapping ; AFLP; microsatellite; synteny; heterochiasmy; recombination; chicken; great reed warbler ; bird; Genetics; cytogenetics; Genetik; cytogenetik; Animal ecology; trait correlation ; Djurekologi; animal model ; selection; Djurs anatomi och morfologi; animal morphology; Animal anatomy; heritability;

   Abstract : Long-term studies of birds play an important role in the understanding of quantitative traits in natural populations. The relative ease by which individual birds can be monitored and caught in the wild enable us collect detailed information from individuals throughout their life time, sometimes from several generations in a population. READ MORE

5. 3. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events

   Author : Robert Piotr Olinski; Finn Hallböök; Mike Thorndyke; Pierre Pontarotti; Uppsala universitet; []
   Keywords : Neurosciences; insulin; relaxin; insulin-like protein; gene duplication; paralogous region; Ciona intestinalis; conserved synteny; ortholog; Drosophila melanogaster; Neurovetenskap;

   Abstract : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. READ MORE

6. 4. Evolution and Pharmacology of Receptors for Bradykinin and Neuropeptide Y in Vertebrates

   Author : Torun Bromée; dan larhammar; Nina Mohell; Samuel Svensson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Pharmacology; Evolution; Neurovetenskap; Neurology; Neurologi;

   Abstract : The bradykinin and neuropeptide Y (NPY) receptors belong to the superfamily of G-protein coupled receptors (GPCRs). The GPCRs form the largest class of therapeutic targets and it is therefore of great interest to investigate the pharmacological properties, functions and evolution of these receptors. READ MORE

7. 5. Probabilistic Modelling of Domain and Gene Evolution

   Author : Sayyed Auwn Muhammad; Jens Lagergren; Bastien Boussau; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Phylogenetics; Phylogenomics; Evolution; Domain Evolution; Gene tree; Domain tree; Bayesian Inference; Markov Chain Monte Carlo; Homology Inference; Gene families; C2H2 Zinc-Finger; Reelin Protein; Computer Science; Datalogi;

   Abstract : Phylogenetic inference relies heavily on statistical models that have been extended and refined over the past years into complex hierarchical models to capture the intricacies of evolutionary processes. The wealth of information in the form of fully sequenced genomes has led to the development of methods that are used to reconstruct the gene and species evolutionary histories in greater and more accurate detail. READ MORE