Search for dissertations about: "synthesis amides"

Showing result 1 - 5 of 42 swedish dissertations containing the words synthesis amides.

  2. 1. New Methodologies in Organic Chemistry: Applications to the Synthesis of α-Amino Acids and Natural Products

    Author : Sebastian Hirner; Peter Somfai; Varinder Aggarwal; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic synthesis; 2-Vinylaziridines; 3-Pyrrolines; Ringexpansion; Rearrangement; Anisomycin; Total synthesis; α-Amino acids; Arylglycines; Weinreb amides; α-Arylation; Grignard reagents; Umpolung; Organic chemistry; Organisk kemi;

    Abstract : This thesis deals with the development and application of new synthetic methodology in organic chemistry. The first part describes the development of a new protocol for the synthesis of 3-pyrrolines by means of a microwave-assisted ring-expansion reaction of 2-vinylaziridines. READ MORE

  4. 2. Iron Carbonyl Mediated Parallel Synthesis

    Author : Henrik Gradén; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dienyl; scavenger; solid phase; galectin inhibitor; oseltamivir; iron carbonyl complex; polymer bound reagent; cation; linker; parallel synthesis; active ester;

    Abstract : This thesis describes the examination and development of cationic iron carbonyl complexes for use in parallel synthesis both in solution phase and on solid phase. A solution phase methodology for carbon-carbon and carbon-heteroatom formation, utilizing polymer bound reagents and scavengers and amenable for automation has been successfully developed. READ MORE

  5. 3. Design and Synthesis of Galectin Inhibitors

    Author : Pernilla Sörme; Barbro Kahl Knutson; U Wellmar; B-G Magnusson; Hakon Leffler; Ulf Nilsson; Yuan C. Lee; Reiko T. Lee; Centrum för analys och syntes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parallel Synthesis; Inhibitors; Biomedicinska vetenskaper allmänt ; General biomedical sciences; Carbohydrates; Galectins;

    Abstract : Galectins, a lectin family, have shown binding affinities towards b-galactosides. Galectins have been proposed to be involved in a wide range of functions like for example, cell growth, adhesion, migration, chemo taxis and apoptosis. They have also been associated with various cancer types. READ MORE

  6. 4. Group (IV) Metal-Catalyzed Direct Amidation : Synthesis and Mechanistic Considerations

    Author : Helena Lundberg; Adolfsson Hans; Tom Sheppard; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; catalysis; amide; carboxylic acid; amino acid; titanium; zirconium; hafnium; organisk kemi; Organic Chemistry;

    Abstract : The amide unit constitutes the backbone of proteins, and it is present in a large number of pharmaceutically active molecules, polymeric materials such as nylon and Kevlar, as well as in food additives like aspartame. Amides are produced in enormous amounts every year, thus, environmentally friendly and selective methods for their formation are of great importance. READ MORE

  7. 5. Building blocks for polymer synthesis by enzymatic catalysis

    Author : Stefan Semlitsch; Mats Martinelle; Sergio Riva; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Enzyme; Enzyme Engineering; Biocatalysis; Lipase; CalB; MsAcT; Substrate specificity; Selectivity; Polymer Chemistry; Polymer Synthesis; Bioteknologi; Biotechnology;

    Abstract : The search for alternatives to oil-based monomers has sparked interest for scientists to focus on the use of renewable resources for energy production, for the synthesis of polymeric materials and in other areas. With the use of renewable resources, scientists face new challenges to first isolate interesting molecules and then to process them. READ MORE