Search for dissertations about: "synthesis compounds"

Showing result 1 - 5 of 575 swedish dissertations containing the words synthesis compounds.

  1. 1. Radiohalogenated Compounds for Tumor Targeting : Synthesis and Radiolabeling

    Author : Eskender Mume; Stefan Sjöberg; Vladimir Tolmachev; D. Scott Wilbur; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; 9-Aminoacridine; Daunorubicin; Doxorubicin; Carborane; Radiobromination; Radioiodination; Affibody; Monoclonal antibody; Oorganisk kemi; Inorganic chemistry; Oorganisk kemi;

    Abstract : This thesis describes the synthesis and radiohalogenation of compounds of potential use for tumor targeting. The first section describes the synthesis and radioiodination of DNA intercalating compounds. The compounds are derivatives of 9-aminoacridine, and the anthracyclins daunorubicin and doxorubicin. READ MORE

  2. 2. Approaches to soft drug analogues of dihydrofolate reductase inhibitors : Design and synthesis

    Author : Malin Graffner Nordberg; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; soft drug; dihydrofolate reductase; synthesis; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Abstract : The main objective of the research described in this thesis has been the design and synthesis of inhibitors of the enzyme dihydrofolate reductase (DHFR) intended for local administration and devoid of systemic side-effects. The blocking of the enzymatic activity of DHFR is a key element in the treatment of many diseases, including cancer, bacterial and protozoal infections, and also opportunistic infections associated with AIDS (Pneumocystis carinii pneumonia, PCP). READ MORE

  3. 3. Open-Framework Germanates and Nickel Germanates : Synthesis and Characterization

    Author : Shiliang Huang; Junliang Sun; Xiaodong Zou; Hermann Gies; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; open-framework; zeolites; germanates; nickel germanates; structure directing agent; nickel complexes; crystal structure determination; hydrothermal synthesis; Structural Chemistry; strukturkemi;

    Abstract : Microporous materials have a wide range of important applications in separation, gas adsorption, ion-exchange and catalysis. Open-framework germanates are a family of microporous compounds and are of particular interest. READ MORE

  4. 4. Synthesis of protic ionic liquids. Challenges and solutions for the synthesis of pure compounds

    Author : Eduardo Maurina Morais; Chalmers University of Technology; []
    Keywords : Protic ionic liquids; Fuel cells; Synthesis; DFT;

    Abstract : The urgent need to diversify our energy matrix is responsible for a renewed interest in fuel cell technology, which can use hydrogen gas, a renewable green fuel, as an energy source. This technology is currently a commercially available option, however, it still requires technological improvements before it can be widely used for different applications. READ MORE

  5. 5. Lignin-carbohydrate complexes: Model compounds synthesis

    Author : Filip Nylander; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lignin-carbohydrate complex; lignin model compounds; lignocellulose;

    Abstract : In lignocellulose there is a recalcitrant interaction by covalent and non-covalent bonds called the lignin-carbohydrate complex. This interaction has been the subject of studies trying to unveil its chemical structure, to understand the mechanims involved in its formation and to determine its influence on practical applications such as the process of turning biomass into ethanol. READ MORE