Search for dissertations about: "synthesis examples"

Showing result 1 - 5 of 91 swedish dissertations containing the words synthesis examples.

  2. 1. Approaches to soft drug analogues of dihydrofolate reductase inhibitors : Design and synthesis

    Author : Malin Graffner Nordberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; soft drug; dihydrofolate reductase; synthesis; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Abstract : The main objective of the research described in this thesis has been the design and synthesis of inhibitors of the enzyme dihydrofolate reductase (DHFR) intended for local administration and devoid of systemic side-effects. The blocking of the enzymatic activity of DHFR is a key element in the treatment of many diseases, including cancer, bacterial and protozoal infections, and also opportunistic infections associated with AIDS (Pneumocystis carinii pneumonia, PCP). READ MORE

  4. 2. Design, synthesis and evaluation of bacterial sialic acid uptake inhibitors

    Author : Tiago Bozzola; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Sialic Acid; antibacterial agents; Medicinal Chemistry; Synthesis; uptake inhibitors;

    Abstract : Antibiotic resistance is a major threat for our society and finding novel antibacterial therapies is of greatimportance. In this thesis, we investigate bacterial sialic acid uptake inhibitors as a novel antibacterial approach.Bacteria do not biosynthesise sialic acid and therefore harvest it from the host. READ MORE

  5. 3. Inorganic and Metal-Organic Framework Materials : Synthesis and structure characterization

    Author : Leifeng Liu; Junliang Sun; Xiaodong Zou; Russell Edward Morris; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray diffraction; transmission electron microscopy; framework materials; porous materials; Inorganic Chemistry; oorganisk kemi;

    Abstract : Inorganic and metal-organic framework materials possessing accessible and permanent pores are receiving tremendous attention. Among them, zeolites are the most famous class due to their wide applications on petrochemistry and gas separation. READ MORE

  6. 4. Background road traffic noise synthesis

    Author : Georgios Zachos; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; background traffic noise synthesis; auralisation; urban sound planning;

    Abstract : As urban planning evolves along with societal life, new requirements that should be met are rising. One of those, is the inclusion of acoustic quality in urban environments, before, during, or after a planning process. To address this for a yet to be built area, metrics are needed that try to quantify acoustic quality. READ MORE

  7. 5. Scheduling and Communication Synthesis for Distributed Real-Time Systems

    Author : Paul Pop; Petru Eles; Zebo Peng; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; distributed embedded systems; hard real-time systems; time-triggered protocol; scheduling; schedulability analysis; communication synthesis; control dependencies; Computer science; Datavetenskap;

    Abstract : Embedded systems are now omnipresent: from cellular phones to pagers, from microwave ovens to PDAs, almost all the devices we use are controlled by embedded systems. Many embedded systems have to fulfill strict requirements in terms of performance and cost efficiency. READ MORE