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Showing result 1 - 5 of 3696 swedish dissertations matching the above criteria.

  2. 1. Stereoselective Synthesis of Amino Alcohols : Applications to Natural Product Synthesis

    Author : Staffan Torssell; Peter Somfai; Pher G Andersson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Amino alcohol; asymmetric 1.3-dipolar cycloaddition; azomethine ylide; carbenoid; carbonyl ylide; cross-metathesis; omuralide; oxazolidine; rhodium; sphingosine; stemoamide; stereoselective synthesis; total synthesis.; Organic chemistry; Organisk kemi;

    Abstract : This thesis is divided into four separate parts with amino alcohols as the common feature. The first part of the thesis describes the development of an efficient three-component approach to the synthesis of α-hydroxy-β-amino esters. READ MORE

  4. 2. Approaches to soft drug analogues of dihydrofolate reductase inhibitors : Design and synthesis

    Author : Malin Graffner Nordberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; soft drug; dihydrofolate reductase; synthesis; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Abstract : The main objective of the research described in this thesis has been the design and synthesis of inhibitors of the enzyme dihydrofolate reductase (DHFR) intended for local administration and devoid of systemic side-effects. The blocking of the enzymatic activity of DHFR is a key element in the treatment of many diseases, including cancer, bacterial and protozoal infections, and also opportunistic infections associated with AIDS (Pneumocystis carinii pneumonia, PCP). READ MORE

  5. 3. Absolute Asymmetric Synthesis

    Author : Anders Lennartson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; absolute asymmetric synthesis; enantioselective synthesis; chirality; optical resolution; spontaneous resolution; conglomerate; organozinc reagents; organometallic chemistry; coordination chemistry; supramolecular chemistry; intermolecular interactions; optical resolution;

    Abstract : Absolute asymmetric synthesis is the synthesis of optically active products from achiral or racemic precursors only. This has generally been regarded as impossible and is relevant in the discussion of the origins of biomolecular homochirality. READ MORE

  6. 4. Parabolic Synthesis

    Author : Erik Hertz; Peter Nilsson; Oscar Gustafsson; Sweden Lund Lund University LTH Department of Electrical and Information Technology Faculty of Engineering; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Many consumer products, such as within the computer areas, computer graphics, digital signal processing, communication systems, robotics, navigation, astrophysics, fluid physics, etc. are searching for high computational performance as a consequence of increasingly more advanced algorithms in these applications. READ MORE

  7. 5. Pheromone Synthesis : Conjugated Diene Systems and Oxygenated Carene Derivatives

    Author : Rikard Unelius; Torbjörn Norin; Lars Skatteböl; KTH Organic Chemistry; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; pheromone diene carene derivative; Organic Chemistry; Organisk kemi;

    Abstract : .... READ MORE