Search for dissertations about: "systemic chemotherapy"
Showing result 1 - 5 of 43 swedish dissertations containing the words systemic chemotherapy.
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1. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer
Abstract : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. READ MORE
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2. Genotoxic effects of systemic chemotherapy in cancer patients, with special focus on the relation between MSI, LOH and development of secondary cancers
Abstract : Systemic chemotherapy results in both phenotypic and genotypic side effects. Genotoxicity posed by chemotherapy is a major concern since it induces DNA damage and instability in the patients’ genome. READ MORE
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3. Combined chemotherapy and immunotherapy against experimental malignant brain tumors
Abstract : Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor in adults. Despite standard treatment including surgery, radiotherapy and temozolomide (TMZ)-based chemotherapy, the prognosis for GBM patients is dismal, and there is a need for novel treatments. READ MORE
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4. Cyclin A and cyclin E as prognostic factors in early breast cancer
Abstract : Breast cancer is one of the most common malignancies in women. Due to early detection and the use of screening programs approximately 60% of all new cases lack lymph node involvement. Today, a substantial proportion of these women will be offered adjuvant systemic chemotherapy. READ MORE
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5. Preclinical Studies for Cryoprevention of Oral Mucositis
Abstract : Oral mucositis (OM) is a debilitating adverse effect, with a prevalence of up to 80% in patients with cancer who are conditioned with high-dose chemotherapy prior to hematopoietic stem cell transplantation. In its mildest form, OM is characterized by erythema. However, as it worsens, it can give rise to painful ulcerations in the oral mucosa. READ MORE