Search for dissertations about: "tablet within tablet"

Showing result 1 - 5 of 14 swedish dissertations containing the words tablet within tablet.

  2. 1. Multivariate Synergies in Pharmaceutical Roll Compaction : The quality influence of raw materials and process parameters by design of experiments

    Author : Nabil Souihi; Johan Trygg; Jukka Rantanen; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Roll compaction; dry granulation; mannitol; dicalcium phosphate; design of experiments; orthogonal projections to latent structures; critical quality attributes; tablet manufacturing; quality by design; design space; near-infrared chemical imaging; texture analysis; modeling; scale up; instrumented roll; Johanson model;

    Abstract : Roll compaction is a continuous process commonly used in the pharmaceutical industry for dry granulation of moisture and heat sensitive powder blends. It is intended to increase bulk density and improve flowability. READ MORE

  4. 2. Drugs and polymers in dissolving solid dispersions : NMR imaging and spectroscopy

    Author : Carina Dahlberg; István Furó; Anna Millqvist-Fureby; Michael Schuleit; Jadwiga Tritt-Goc; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical chemistry; Fysikalisk kemi; Surface and colloid chemistry; Yt- och kolloidkemi; PHARMACY; FARMACI;

    Abstract : The number of poorly water-soluble drug substances in the pharmaceutical pipeline is increasing, and thereby also the need to design effective drug delivery systems providing high bioavailability. One favourable formulation approach is preparation of solid dispersions, where dispersing a poorly water-soluble drug in a water-soluble polymer matrix improves the dissolution behaviour and the bioavailability of the drug. READ MORE

  5. 3. Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release

    Author : Patrik Knöös; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drug deliver; Controlled release; Hydrophobically modified polymers; Surfactant-polymer interactions; Poorly soluble drug;

    Abstract : An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. READ MORE

  6. 4. Additive Manufacturing and Mesoporous Materials for Pharmaceutical Applications

    Author : Christos S. Katsiotis; Ken Welch; Jonas Lindh; Maria Stromme; Ryan Donnelly; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Additive Manufacturing; Fused Deposition Modelling; Semi Solid extrusion; Mesoporous materials; Poorly water soluble drugs; Drug delivery; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

    Abstract : Additive Manufacturing (AM), over the past decade, has evolved into a versatile technology with significant applications in pharmaceutical research. This technology enables the production of drug formulations tailored to individual patients, offering customization in both dosage and dissolution profiles. READ MORE

  7. 5. Separation of Pharmaceuticals by Capillary Electrophoresis using Partial Filling and Multiple-injections

    Author : Henrik Lodén; Curt Pettersson; Torbjörn Arvidsson; Ahmad Amini; Morgan Stefansson; Uppsala universitet; []
    Keywords : Capillary Coating; Chiral Separation; Enantiomers; Mass-spectrometric Detection; Method Validation; Multiple-injection Capillary Zone Electrophoresis; Non-aqueous Capillary Electrophoresis; Organic Solvents; Pharmaceutical Analysis; Quantitative Analysis;

    Abstract : Different multiple-injection methodologies and the partial filling technique (PFT) have been utilized for separation of pharmaceuticals by capillary elec-trophoresis. In multiple-injection capillary zone electrophoresis (MICZE), the samples and all standards, used for construction of the calibration curve, are analyzed within a single run. READ MORE