Search for dissertations about: "tablets"

Showing result 16 - 20 of 107 swedish dissertations containing the word tablets.

  2. 16. Dissolution and Release Behavior of Swellable Matrix Tablets: Influence of the solubility and dissolution rate enhancement of model substance

    Author : Farhad Tajarobi; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Tablets exhibiting extended drug release have in many therapeutical applications shown both compliance and clinical advantages. One way of achieving extended drug release from a tablet is by employing the concept of swellable matrices. READ MORE

  4. 17. Dissolution of Polydisperse Polymers in Water

    Author : Anna Körner; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysikalisk kemi; Physical chemistry; PEO; swelling; polymer dissolution; polydispersity;

    Abstract : The different steps in the dissolution process of polydisperse polymers in water have been studied. To that end, poly(ethylene oxide), dextran and hydroxypropyl methylcellulose tablets varying widely in polydispersity have been produced by mixing low molecular weight and high molecular weight samples in different proportions. READ MORE

  5. 18. Particle interactions and internal tablet structure : Factors affecting the mechanical strength of pharmaceutical compacts

    Author : Helena Olsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : A simple tablet model was utilised to identify parameters responsible for tablet compactibility. In this model tablets were considered as homogeneous and isotropic aggregates of individual spherical particles. If the particles were located close enough to each other, interparticulate bonds were assumed to be developed. READ MORE

  6. 19. Compression mechanics of pharmaceutical aggregates : Studies on the tabletting of spheronised aggregates with varying composition and porosity

    Author : Fredrik Nicklasson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : The thesis investigated the tabletting behaviour of aggregates of different porosity and material composition, and focused on the role of the compression mechanics of the aggregates as a link between their structure and composition and the structure and functionality of tabletsformed from them. The aggregates studied all responded to compression by deformation and densification. READ MORE

  7. 20. Multivariate methods in tablet formulation

    Author : Jon Gabrielsson; Michael Sjöström; Svante Wold; Torbjörn Lundstedt; Marc Brown; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; PCA; statistical experimental design; multivariate design; PLS; excipients; direct compression; tablet formulation; robustness testing; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes the application of multivariate methods in a novel approach to the formulation of tablets for direct compression. It begins with a brief historical review, followed by a basic introduction to key aspects of tablet formulation and multivariate data analysis. READ MORE