Search for dissertations about: "tag arrays"

Showing result 6 - 10 of 10 swedish dissertations containing the words tag arrays.

  2. 6. Validation of antibodies for protein profiling : A study using immunohistochemistry on tissue microarrays

    Author : Linda Paavilainen; Fredrik Pontén; Ola Nilsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody validation; monospecific antibodies; protein profiling; immunohistochemistry; tissue microarrays; western blot; fixatives; Pathology; Patologi; Pathology; patologi;

    Abstract : The field of proteomics has rapidly expanded due to the completion of the human genome sequence. This thesis validates affinity-purified monospecific antibodies of polyclonal origin, for protein profiling in a broad spectrum of normal tissues and cells. READ MORE

  4. 7. Gene complexes and regulatory domains in metazoan genomes

    Author : Pär Engström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Despite the recent massive increases in genome and transcript sequence data, including wholegenome sequences for humans and many other metazoans, our understanding of the content of these sequences is far from complete. This thesis is about making use of metazoan sequence data to detect functional genetic elements on a genome-wide scale and examine the distribution of those elements on chromosomes. READ MORE

  5. 8. Nanoscopic adventures : unraveling macromolecular complexes in infectious diseases via integrative structural biology

    Author : Kai Patric Ehrenbolger; Ronnie Berntsson; Felipe Cava; Jonas Barandun; David Drew; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Infectious diseases; E. faecalis; Microsporidia; Ribosome; Proteasome; Polar Tube; Structural Biology; Single particle Cryo-Electron Microscopy;

    Abstract : This thesis focuses on understanding the underlying molecular mechanisms of infectious diseases, which claim nearly 9 million lives annually. The research centers on critical analysis of pathogen mechanisms and drug resistance. I have mainly focused on two clades of pathogens: Enterococcus faecalis and microsporidia. E. READ MORE

  6. 9. Genome and Transcriptome Analyzes in the Ectomycorrhizal Fungus Paxillus involutus

    Author : Antoine Le Quéré; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mikrobiologi; bakteriologi; virologi; mykologi; virology; mycology; bacteriology; Microbiology; Genome Transcriptome Ectomycorrhiza Paxillus-involutus microarray;

    Abstract : Mycorrhizal symbioses are formed between plant root systems and compatible fungal hyphae that results in a complex mixed structure. They are found in all ecosystems and with the majority of land plants such as forest trees or crops that are of commercial interest. READ MORE

  7. 10. Nanowires for Cell Research

    Author : Waldemar Hällström; Fasta tillståndets fysik; []
    Keywords : Nanotoxicology; Nanowires; Nanotubes; Nerve Cells; Cell Probing; Force Measurements; Nanotechnology; Axonal Guidance; Fysicumarkivet A:2010:Hällström;

    Abstract : This study explores the interaction between living biological cells and semiconductor nanowires. Biological cells are highly complex and dynamic entities, every one of them with individual characteristics and a high degree of internal and external communication. READ MORE