Search for dissertations about: "target engagement-mediated amplification"

Found 1 swedish dissertation containing the words target engagement-mediated amplification.

2. 1. Molecular Approaches to Explore Drug-Target Interactions

   Author : Abdullah Al-Amin; Ulf Landegren; Christopher Schofield; Uppsala universitet; []
   Keywords : Drug discovery; target engagement; target engagement-mediated amplification; cellular thermal shift assay; proximity extension assay; in situ PLA; high-content imaging; Molekylär medicin; Molecular Medicine;

   Abstract : Improved means to assess the clinical potential of drug candidates can critically influence development of new therapeutic entities, a central aim in medical life science. Drug discovery and development relies on construction and selection of small organic compounds or biological agents that bind targets of interest. READ MORE