Search for dissertations about: "target orthogonal partial least squares"
Found 3 swedish dissertations containing the words target orthogonal partial least squares.
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1. Exploration of Multivariate Evaluation Techniques in Surface Enhanced Raman Spectroscopy (SERS)
Abstract : .... READ MORE
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2. Epidemiology and statistical modeling in burn injuries
Abstract : An important issue in assessing the epidemiology of injuries, including burns, is the investigation of appropriate methodologies and statistical modeling techniques to study injuries in an efficient and trustworthy manner. The overall aim of this thesis is to analyze epidemiological patterns and assess the appropriateness of supervised statistical models to investigate burn risks and patterns. READ MORE
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3. Molecular mechanisms and targets of new anticancer treatments
Abstract : The work presented in this thesis is an effort to decipher and understand the mechanism of action (MOA) of anticancer agents by building on and complementing chemical proteomics methods. The backbone of the thesis relies on a recent method called Functional Identification of Target by Expression Proteomics (FITExP) developed in Zubarev lab, where drug induced proteomic signatures are analyzed in various cell lines and top differentially regulated proteins with consistent behavior are determined, among which the drug target and mechanistic proteins are usually present. READ MORE