Search for dissertations about: "targeted therapy"
Showing result 21 - 25 of 323 swedish dissertations containing the words targeted therapy.
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21. Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy
Abstract : Metastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecular determinants of metastasis, breast cancer relapse and death rates remain unacceptably high. READ MORE
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22. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery
Abstract : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. READ MORE
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23. Affibody molecules targeting HER3 for cancer therapy
Abstract : The development of targeted therapy has contributed tremendously to the treatment of patients with cancer. The use of highly specific affinity proteins to target cancer cells has become a standard in treatment strategies for several different cancers. READ MORE
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24. Staging and therapy response in rectal cancer
Abstract : Every year, around 2,200 individuals are diagnosed with rectal cancer in Sweden. As a result of better tumour staging using magnetic resonance imaging (MRI), pre-operative radiotherapy (with or without chemotherapy), and improved surgery, outcome has improved substantially during the past few decades. READ MORE
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25. PNA and affinity protein tools for selective tumor targeting of radiopharmaceuticals
Abstract : Targeted radiotherapy of cancer intends to selectively deliver cytotoxic radionuclides to tumor cells. Affinity proteins of various kinds are explored for this task, and depending on the affinity protein used, different challenges arise. READ MORE