Search for dissertations about: "tautomerase"

Found 3 swedish dissertations containing the word tautomerase.

  2. 1. Quantum chemical modeling of enzymatic reactions : applications to the tautomerase superfamily

    Author : Robin Sevastik; Fahmi Himo; Margaretha Blomberg; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioengineering; Bioteknik;

    Abstract : In this thesis, quantum chemical methods are used to investigate enzymatic reaction mechanisms. The Density functional theory, in particular the hybrid B3LYP functional, is used to model two enzymes belonging to the tautomerase superfamily; 4-Oxalocrotonate Tautomerase (4-OT) and cis-Chloroacrylic Acid Dehalogenase (cis-CAAD). READ MORE

  4. 2. Analysis of melanins

    Author : Gerd Odh Olsson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PPT-II; PPT-I; DDT; MIF; tyrosinase related protein. dopachrome tautomerase; 3-dicarboxylic acid; pyrrole-2; 5-tricarboxylic acid; 3; thiazole-4; 5-dicarboxylic acid; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : Mammalian melanins are of two major types, eumelanins and peheomelanins, which often occur together, then called mixed-type melanins. A method has been developed for analysing the various forms of melanins. READ MORE

  5. 3. Development of a protein-free fed-batch process for NS0 cells: studies on regulation of proliferation

    Author : Erika Spens; Lena Häggström; Jean-Louis Goergen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NS0 myeloma cells; protein-free medium; fed-batch; conditioned medium; autocrine growth factors; abortive proliferation; protease activity; aprotinin; gp130; Bioengineering; Bioteknik;

    Abstract : The overall objective of this study was to investigate how NS0 cell proliferation is regulated in protein-free media. The hypothesis was that during the adaptation to growth factor-free media, animal cell lines start to produce their own autocrine growth factors to support proliferation, and after some time in a culture the effects of these factors are lost which results in cessation of proliferation. READ MORE