Search for dissertations about: "technetium"

Showing result 1 - 5 of 19 swedish dissertations containing the word technetium.

  1. 1. Molecular Radionuclide Imaging Using Site-specifically Labelled Recombinant Affibody Molecules Preparation and Preclinical Evaluation

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sara Ahlgren; Vladimir Tolmachev; Anna Orlova; Göran Hedenstierna; Joachim Feldwisch; Raymond Reilly; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular radionuclide imaging; Affibody molecules; HER2; cancer detection; radiolabelling; technetium; indium; cobalt; SPECT; PET; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; MEDICINE Physiology and pharmacology Radiological research Diagnostic radiology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Diagnostisk radiologi; MEDICINE Physiology and pharmacology Radiological research Radiation biology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Strålningsbiologi; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap; Medicinsk vetenskap; Medical Science;

    Abstract : Radionuclide molecular imaging is an emerging multidisciplinary technique that is used in modern medicine to visualise diseases at cellular and molecular levels. This thesis is based on five papers (I-V) and focuses on the development of site-specific radiolabelled recombinant anti-HER2 Affibody molecules and preclinical evaluations in vitro and in vivo of the labelled conjugates. READ MORE

  2. 2. Studies of Long-lived Radionuclides in the Environment - with Emphasis on 99Tc, 237Np and Pu Isotopes

    University dissertation from Patric Lindahl, Department of Radiation Physics, University Hospital, 221 85 Lund, Sweden

    Author : Patric Lindahl; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; atomic ratio; environmental samples; nuclear weapons fallout; Chernobyl fallout; bioindicators; activated carbon; Sellafield; plutonium; neptunium; ICP-MS; technetium;

    Abstract : Studies of the long-lived anthropogenic radionuclides 99Tc, 237Np, 239Pu and 240Pu were performed in marine and terrestrial areas contaminated by different accidental and controlled releases of radioactive materials. The three main sources discussed in this thesis are nuclear weapons tests, nuclear reprocessing plants and the Chernobyl accident. READ MORE

  3. 3. Deposition and absorption of inhaled drugs

    University dissertation from Department of Clinical Physiology, Lund University

    Author : Eva Bondesson; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; technetium-99m; radionuclide imaging; radioactive aerosol; powder inhaler; pharmacokinetics; mucociliary clearance; lung deposition; gamma scintigraphy; inhalation; deposition modelling; drug absorption; absorption enhancer; aerosol; medicinsk instrumentering; Physiology; Fysiologi;

    Abstract : Main objectives of this thesis were to evaluate a gamma scintigraphic method used to quantify drug aerosol deposition in the lung, to investigate the influence of two aerosol inhalation parameters on the distribution of inhaled dry powder within the airways, to assess pulmonary absorption kinetics and bioavailability of an inhaled hydrophilic solute in relation to site of deposition, and to assess the influence of a surface active agent (sodium taurocholate, a bile salt) on the deposition and absorption of an inhaled hydrophilic solute. Repeated planar gamma scintigraphy was found to provide the same information on total pulmonary drug deposition as an independent method that involved assessments of urinary drug recovery after blockage of gastrointestinal drug absorption when all of the critical parts of the methodological procedures were accurately and meticulously executed. READ MORE

  4. 4. Endothelial cell seeding and the thrombogenicity of vascular grafts

    University dissertation from Dept of Surgery, Centralsjukhuset, 65185 Karlstad. Karlstad

    Author : Norman Jensen; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; humans.; sheep; Iodine-125; Technetium-99m; Indium-111; TxA2; PGI2; fibrinogen; leukocyte; platelet; cell seeding; Blood vessel prosthesis; endothelium; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : ABSTRACT In humans, synthetic vascular grafts heal with a limited ingrowth of endothelium. This fact might be responsible for inferior performance of synthetic grafts compared with native artery.Endothelial cells can be autotransplanted (seeded) into the graft in an effort to improve graft function. READ MORE

  5. 5. Tick-borne encephalitis : on pathogenesis and prognosis

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Göran Günther; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human; tick-borne encephalitis; viral; meningo-encephalitis; cerebrospinal fluid; PCR; cytokines; immunoglobulin; SPECT; technetium-99m-HMPAO;

    Abstract : The general aim of the five studies presented in this thesis was to investigate the clinical oucome and prognosis and factors of importance for the pathogenesis of TBE compared to other aseptic meningo encephalitis. In a prospective study 149 patients presenting with clinical symptoms of acute viral meningo-encephalitis between June 1991 and December 1993 were included. READ MORE