Search for dissertations about: "telomere length"

Showing result 1 - 5 of 38 swedish dissertations containing the words telomere length.

  1. 1. Telomere length dynamics and role as a biological marker in malignancy

    University dissertation from Umeå : Umeå University

    Author : Ulrika Svenson; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Telomere length; peripheral blood; immune cells; breast cancer; renal cell carcinoma; biological marker; patologi; Pathology;

    Abstract : Telomeres are protective structures at the end of our chromosomes, composed of multiple repeats of the DNA sequence TTAGGG. They are essential for maintaining chromosomal stability by preventing damage and degradation of the chromosome ends. READ MORE

  2. 2. Exposure, telomere length, and cancer risk

    University dissertation from Lund University

    Author : Huiqi Li; Lunds universitet.; Lund University.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; exposure; telomere; methylation; chromosomal aberration; cancer risk; rubber fumes; arsenic; welding fumes; diesel exhaust; particulate matter;

    Abstract : Telomeres are tandem repeats of TTAGGG at the end of eukaryotic chromosomes. Telomeres play a key role in chromosome stability and regulation of the cellular lifespan. Telomeres are shortened during cell division, and probably, by not yet well characterised factors in the environment. READ MORE

  3. 3. LIVING WITH PARASITES: AVIAN MALARIA, TELOMERE LENGTH AND LIFE HISTORY TRADE-OFFS

    University dissertation from Department of Biology, Lund University

    Author : Asghar Muhammad; Lunds universitet.; Lund University.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Avian malaria; Plasmodium; qPCR; parasitemia; life history; reproduction; survival; feather growth; MHC; telomere length; heritability; telomere loss; fitness; wild population; Acrocephalus arundinaceus; Delichon urbica;

    Abstract : Popular Abstract in English Parasites and their host organisms have engaged in a desperate battle over millions of years to evolve strategies that enable continued survival of their respective species. Parasites require some key metabolites to be able to survive and reproduce inside the host that often results in damage to host, while host organisms attempt to limit or prevent this damage by several ways including behavioral changes and building costly immune defences. READ MORE

  4. 4. Telomere length - inheritance pattern and role as a biomarker

    University dissertation from Umeå : Medicinsk biovetenskap

    Author : Katarina Nordfjäll; Umeå universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; telomere length; peripheral blood; inheritance; breast cancer; survival; polymorphism; MEDICINE Morphology; cell biology; pathology Cell biology Medical cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Medicinsk cellbiologi;

    Abstract : Telomeres are repetitive TTAGGG structures ending each chromosome and thereby protecting its integrity. Due to the end-replication problem, telomeres shorten with each cell division. When reaching a critical telomere length (TL), the cells stop dividing and enter replicative senescence. READ MORE

  5. 5. Telomere length as prognostic parameter in chronic lymphocytic leukemia

    University dissertation from Umeå : Umeå University

    Author : Pawel Grabowski; Umeå universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; telomere length; chronic lymphocytic leukemia; prognosis; longitudinal sampling; genomic aberrations; IGHV; CD38; ZAP70; prognostic factors; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi; patologi; Pathology;

    Abstract : B-cell chronic lymphocytic leukemia (B-CLL) is the most common leukemia among the adult population in western countries and accounts for 30-40% of all leukemias. With survival time ranging from months to decades, the clinical course of individual CLL patients is highly variable. READ MORE