Search for dissertations about: "thapsigargin"

Showing result 1 - 5 of 11 swedish dissertations containing the word thapsigargin.

  2. 1. Protein expression analysis of insulin producing cells exposed to endoplasmic reticulum stress

    Author : Victoria Rosengren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The prevalence of type 2 diabetes mellitus (T2DM) is increasing rapidly as a result of the obesity epidemic. T2DM develops in individuals who fails to compensate for increased demand of insulin. READ MORE

  4. 2. Regulation of T cell apoptosis by calcium and zinc ions

    Author : Shunai Jiang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Apoptosis is a major form of cell death involved in fundamental processes in the mammalian immune system. Although extensive studies have been carried out to explore the mechanisms involved in lymphocyte apoptosis, a defined signaling pathway is still unclear. READ MORE

  5. 3. Studies of the device perfect capsule in an animal model to reduce lens epithelial cell proliferation

    Author : Mahmoud Taie Abdelwahab; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The sealed-capsule irrigation device, the Perfect Capsule, is a surgical device designed to target lens epithelial cells (LECs) during cataract surgery and prevent posterior capsule opacification (PCO). This is especially important in cases in which the posterior capsule must stay intact after cataract surgery, such as when implanting accommodative lenses. READ MORE

  6. 4. Regulation of human eosinophil transmigration across lung epithelium

    Author : Lixin Liu; Uppsala universitet; []
    Keywords : Medical sciences; Eosinophils; regulation; migration; epithelial cells; lung; calcium; CD11b CD18; neutrophils; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Abstract : Eosinophil infiltration into the lung tissues and airways is a hallmark of allergic asthma. To reach the lung lumen, eosinophils migrate across the vascular endothelium, through the interstitial matrix and across lung epithelium. READ MORE

  7. 5. Roles of the transient receptor potential channels and the intracellular Ca2+ channels in Ca2+ signaling in the beta-cells

    Author : Amanda Jabin Fågelskiöld; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ca2 signaling;

    Abstract : Previous studies from our group reported that pancreatic β-cells express ryanodine receptors (RyRs) that can mediate Ca2+-induced Ca2+ release (CICR). The full consequences of the activation of RyRs on Ca2+ signaling in these cells, however, remained unclear. READ MORE