Search for dissertations about: "the orphan"

Showing result 1 - 5 of 71 swedish dissertations containing the words the orphan.

  2. 1. The orphan : tragic form in Thomas Otway

    Author : Kerstin Lund-Baer; Uppsala universitet; []
    Keywords : HUMANIORA; HUMANITIES; English language; Engelska språket;

    Abstract : .... READ MORE

  4. 2. Orphan Genes Bioinformatics : Identification and properties of de novo created genes

    Author : Walter Basile; Arne Elofsson; Diethard Tautz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; de novo; orphans; evolutionary genetics; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Even today, many genes are without any known homolog. These "orphans" are found in all species, from Viruses to Prokaryotes and Eukaryotes. For a portion of these genes, we might simply not have enough data to find homologs yet. READ MORE

  5. 3. Unlocking the Role Of Orphan Solute Carrier SLC38A10 In Brain Metabolism : The SLC38A10 transporter in nutrient and metabolic regulation

    Author : Rekha Tripathi; Robert Fredriksson; Manuel Palacín; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solute carrier; SLC38A10 transporter; SLC38 family; ER Golgi localization; Amino acid starvation; Nutrient sensing; mTOR signaling; Transcriptomic; Protein array; Metabolomics; Ingenuity Pathway Analysis; Farmaceutisk vetenskap; Pharmaceutical Science; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Membrane transporters are the primary gatekeepers of cells and regulate the transport of nutrients, metabolites, ions, water, and neurotransmitters into and across the human cells. The solute carrier transporters (SLCs) are the most prominent transporters, comprising 430 members divided into 65 subfamilies. READ MORE

  6. 4. Discovery of Novel Receptors for Lipid Mediators - a study leading to the identification of receptors involved in metabolism and the immune system

    Author : Niclas Nilsson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; Thiazolidinedione; SCFA; FFA; FFA2R; FFA1R; GPR43; GPR41; GPR40; BLT2; GPCR; Orphan; Receptor;

    Abstract : Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. READ MORE

  7. 5. Studies on the atypical orphan receptor SHP

    Author : Lotta Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nuclear receptors (NRs) comprise the largest family of transcription factors in eukaryotes and play critical roles in nearly every aspect of vertebrate development and adult physiology. In general, they function as transcriptional regulators that when bound to DNA either activate or suppress target gene expression. READ MORE