Search for dissertations about: "therapeutic gain"

Showing result 1 - 5 of 122 swedish dissertations containing the words therapeutic gain.

  2. 1. ARCON in experimental and clinical radiotherapy

    Author : Ana Maria Rojas Callejas; Björn Zackrisson; René-Olivier Mirimanoff; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; ARCON; tumours; normal tissues; radiosensitization; carbogen; nicotinamide; repair inhibition; therapeutic gain; rodents; humans; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Abstract : xHypoxia and repopulation of tumour clonogens are two important determinants of treatment outcome in radiotherapy. In general clinical evidence indicates that loco-regional control may be reduced with long overall treatment times and for tumours with low pre-treatment levels of oxygen. READ MORE

  4. 2. Novel therapeutic targets in pediatric neural tumors

    Author : Jelena Milosevic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The embryonal tumors neuroblastoma and medulloblastoma are two of the most common and deadliest tumors in childhood. Both are heterogeneous tumors that arise in the peripheral and central nervous system, respectively. READ MORE

  5. 3. Prostasomes as Diagnostic, Prognostic and Therapeutic Vesicles

    Author : Louise Dubois; Anders Larsson; Lucia Mincheva-Nilsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exosomes; Prostasomes; Lipid rafts; Bioengineered vesicles; Prostate cancer; Purinergic receptors; Thymidine kinase 1; Medical Biochemistry; Medicinsk biokemi;

    Abstract : This thesis explores prostasomes and their ability to be used as a new diagnostic tool for prostate cancer. Alongside diagnosis, this thesis also suggests prostasomes as a tool for prognosis and therapeutic treatment in patients with prostate cancer. READ MORE

  6. 4. α1-microglobulin – Therapeutic opportunities in kidney and erythrocyte pathology

    Author : Amanda Kristiansson; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; α1-microglobulin; oxidative stress; kidneys; heme; Red blood cells; hemolysis; radiation;

    Abstract : Oxidative stress is defined as an imbalance between oxidants and antioxidants. The reasons behind the condition are diverse, and can result in, or contribute to, the severity of many diseases. The body has different protective mechanisms to reduce the oxidative burden, among them a protein called α1-microglobulin (A1M). READ MORE

  7. 5. Computed tomography in endodontic decision making

    Author : Fernando José Mota de Almeida; Malmö universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endodontics; decision making; computed tomography; CBCT; cone beam; interviews; qualitative content analysis; diagnostic thinking efficacy; therapeutic efficacy;

    Abstract : Computed tomography has been used in dentistry as a complement to two-dimensional (2D) imaging since the 1980s. The advent of cone beam computed tomography (CBCT), a more modern computed tomog-raphy technique, meant a revolution in dento-maxillofacial imaging due to sharper images, with less radiation and at a lower cost than with mul-ti-slice computed tomography (MSCT), i. READ MORE