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Showing result 1 - 5 of 212 swedish dissertations matching the above criteria.
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1. Biophysical aspects of the skin barrier : towards increased non-invasive extraction and optimized biomarker sampling
Abstract : The skin provides a link to the body’s health via its rich variety of high and low molecular weight biomarkers, reflecting both systemic diseases (e.g., cancer, diabetes) and local skin disorders (e.g. READ MORE
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2. Aseptic Loosening of Orthopedic Implants : Osteoclastogenesis Regulation and Potential Therapeutics
Abstract : Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. READ MORE
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3. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies
Abstract : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. READ MORE
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4. Living with Lewy body dementia. Treatment, survival & quality of life
Abstract : Background: Patients with Lewy body dementias (LBD) have a complex clinical picture. With no prevention or cure, management focuses around symptomatic relief, however pharmacological and non-pharmacological options have been inadequately investigated. READ MORE
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5. Extracellular Vesicles and RNA interference in tumors
Abstract : Extracellular vesicles (EVs) including apoptotic bodies (ABs), microvesicles (MVs), exosomes (EXOs) and cell derived artificial nanovesicles (NVs) are important mediators of cell-to-cell communication, in part by transferring bioactive molecules such as DNA, mRNA, miRNA, siRNA, proteins, and lipids. These EVs are released by many cell types, including melanoma cells, and are found in many body fluids. READ MORE