Search for dissertations about: "thermodynamics in enzyme catalysis"
Showing result 1 - 5 of 7 swedish dissertations containing the words thermodynamics in enzyme catalysis.
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1. On Catalytic Mechanisms for Rational Enzyme Design Strategies
Abstract : Enzymes enable life by promoting chemical reactions that govern the metabolism of all living organisms. As green catalysts, they have been extensively used in industry. However, to reach their full potential, engineering is often required, which can benefit from a detailed understanding of the underlying reaction mechanism. READ MORE
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2. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry
Abstract : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. READ MORE
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3. Redox Reactions of NO and O2 in Iron Enzymes : A Density Functional Theory Study
Abstract : In the present thesis the density functional B3LYP has been used to study reactions of NO and O2 in redox active enzymes.Reduction of nitric oxide (NO) to nitrous oxide (N2O) is an important part in the bacterial energy conservation (denitrification). READ MORE
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4. Enzyme substrate solvent interactions : a case study on serine hydrolases
Abstract : Reaction rates and selectivities were measured for transacylation of fatty acid esters in solvents catalysed by Candida antarctica lipase B and by cutinase from Humicola insolens. With these enzymes classical water-based enzymology can be expanded to many different solvents allowing large variations in interaction energies between the enzymes, the substrates and the surrounding. READ MORE
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5. Sequence- and structure guided engineering of proteins and enzymes for biotechnology and health applications
Abstract : Proteins are highly diverse and sophisticated biomolecules that represent a cornerstone of biological structure and function and have been exploited in man-made applications for thousands of years. Those proteins that facilitate chemical reactions at physiologically relevant time-scales are referred to as enzymes. READ MORE