Search for dissertations about: "thesis carcinoma breast"

Showing result 11 - 15 of 92 swedish dissertations containing the words thesis carcinoma breast.

  2. 11. Cell cycle perspectives on breast cancer cell behaviour

    Author : Pontus Berglund; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; invasion; breast cancer; migration; proliferation; cyclin D1; cyclin E;

    Abstract : Uncontrolled proliferation and the capacity to infiltrate surrounding tissues are two important characteristics of aggressive tumour cells. Previous observations in both colorectal cancer and basal cell carcinoma indicated that infiltrative tumour cell behaviour might be counteracted by a high proliferative activity, suggesting a coordination of these two activities at the cellular level. READ MORE

  4. 12. Molecular factors influencing epithelial-mesenchymal transition in breast cancer

    Author : Gisela M A Nilsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; epithelial-mesenchymal transition; c-erbB2; E-cadherin; NFI-C2; FoxF1; LOX;

    Abstract : Epithelial-mesenchymal transition (EMT) is a developmental process defined by loss of epithelial characteristics and acquisition of mesenchymal phenotype. EMT or similar processes are also implicated in carcinoma cell invasion and the progression of breast carcinoma to metastasis. READ MORE

  5. 13. ANALYSIS OF NOVEL BIOMARKERS FOR UNFAVORABLE BREAST CANCER PROGNOSIS

    Author : Emman Shubbar; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ductal Carcinoma In Situ DCIS ; Primary invasive breast cancer; Biomarkers;

    Abstract : Breast cancer is the most common malignancy in women, and a major cause of mortality and morbidity despite the advances in diagnosis and treatment. The main challenge remains to identify novel biomarkers in order to improve existing treatment modalities. Ductal carcinoma in situ (DCIS) is considered as a direct precursor of invasive breast cancer. READ MORE

  6. 14. High-risk breast cancer: From biology to personalized therapeutic strategies

    Author : Toshima Z Parris; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; outcome prediction; molecular biomarker; 8p11-p12 amplification;

    Abstract : Adjuvant treatment regimens for breast cancer are primarily based on patient- and tumor-related factors, e.g. patient menopausal status, tumor stage and histological grade, and the status of molecular tumor markers (HER2/neu and the estrogen receptor). READ MORE

  7. 15. The risk of second primary lung carcinoma in breast cancer patients

    Author : Michaela Prochazka; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Breast cancer; second primary malignancy; lung cancer; radiotherapy; smoking; validation study; familial risk;

    Abstract : The overall aim of this thesis was to investigate the risk of second primary malignancies - with a special focus on lung cancer - in a cohort of approximately 152,000 Swedish women diagnosed with breast cancer between 1958 and 2000. With recent advances in early diagnosis and treatment, breast cancer is becoming an increasingly survivable disease. READ MORE