Search for dissertations about: "thesis for brain oncology"
Showing result 6 - 10 of 68 swedish dissertations containing the words thesis for brain oncology.
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6. Risk and prognostic factors for malignant glioma
Abstract : Background: Glioblastoma is the most common and aggressive type of glioma and associated with poor prognosis. Apart from ionizing radiation and some rare genetic disorders, few aetiological factors have been identified for primary brain tumours. READ MORE
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7. Significance of white matter anatomy in interpreting features and behaviour of low-grade gliomas and implications for surgical treatment
Abstract : Diffuse gliomas are extremely heterogeneous tumours characterized by slow growth but extensive infiltration. Their kinetic features reflect the complex interaction over time with the surrounding brain, influencing treatment planning and outcome. READ MORE
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8. From Genes to Therapy : Modeling and Novel Therapeutic Strategies for Brain Tumors
Abstract : Medulloblastoma is the most common malignant pediatric brain tumor and is molecularly divided into four subgroups – WNT, SHH, Group 3 and Group 4. Two thirds of medulloblastoma patients survive, but survivors often suffer from severe, lifelong side-effects. The MYCN oncogene is deregulated in many medulloblastoma patients. READ MORE
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9. Studies on the biological functions of interaction between components in Wnt, TGF-β and HIF pathways for cancer progression
Abstract : Cancer is a disease that involves aggressive changes in the genome and aberrant signals between the living cells. Signalling pathways such as TGF-β (Transforming growth factor-β), Wnt, EGF (epidermal growth factor) and HIF (Hypoxia-inducible factor) evolved to regulate growth and development in mammals. READ MORE
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10. Molecular and physiological functions of LRIG proteins and netrin-1 in health and disease
Abstract : The leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family has three members, LRIG1, LRIG2, and LRIG3, that encode three structurally similar transmembrane proteins. LRIG1 is a receptor tyrosine kinase regulator, tumor suppressor, and stem cell marker in the skin, intestine, and brain. READ MORE