Search for dissertations about: "thesis for cancer and chemotherapy"

Showing result 1 - 5 of 420 swedish dissertations containing the words thesis for cancer and chemotherapy.

  2. 1. LOAd703 and beyond : Advancing immunostimulatory gene therapy for cancer

    Author : Jessica Wenthe; Angelica S. Loskog; Marco Donia; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Immunotherapy; Gene therapy; Oncolytic virus; Adenovirus; CAR T cells; Immune checkpoint inhibition; CD40L; 4-1BBL; IL-2;

    Abstract : In the last decade, immunotherapy has come into the limelight of cancer treatments. Immunotherapy aims to stimulate the body’s own immune system to create or reinvigorate anti-tumor immune responses. READ MORE

  4. 2. Aspects of Chemotherapy in Prostate Cancer

    Author : Åsa Jellvert; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; CRPC; chemotherapy; metronomic; prognostic; predictive; biomarkers;

    Abstract : Since 2004 chemotherapy has been a part of standard of care in prostate cancer (PC) and improved symptom control and survival has been demonstrated in metastatic castration-resistant PC. Whether docetaxel has benefits in earlier stages of PC is currently under investigation. READ MORE

  5. 3. The proteasome as a target for cancer therapy

    Author : Peter Larsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Cell viability assay; Chemotherapy; Drug repurposing; Genomic and transcriptomic signatures; Prognostic biomarkers; Proteasome; Proteasome genes; Proteasome inhibitors; Drug sensitivity biomarkers; Synergistic effect; Triple-negative breast cancer;

    Abstract : The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The proteasome (PSM) plays an important role in maintaining cellular proteostasis and degrades the majority of proteins that require breakdown in the cell. READ MORE

  6. 4. Mismatch repair deficiency in colorectal cancer : prognosis and prediction for basic treatment strategies

    Author : Ioannis Gkekas; Jan Novotny; Karin Strigård; Richard Palmqvist; Ulf Gunnarsson; Christian Sturesson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; defective mismatch repair; prognosis and prediction; Oncology; onkologi;

    Abstract : Colorectal cancer (CRC) remains a significant healthcare problem worldwide, being the third most common cancer and the fourth most frequent cause of cancer death. Environmental and dietary factors such as alcohol abuse, cigarette smoking, and genetic predisposition seem to constitute the main aetiologies. READ MORE

  7. 5. Neoadjuvant chemotherapy in muscle-invasive urinary bladder cancer : studies on treatment response, tumor draining lymph nodes and blood transfusion

    Author : Robert Rosenblatt; Amir Sherif; Ola Winqvist; Per Marits; Ralph Peeker; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bladder cancer; neoadjuvant chemotherapy; tumor downstaging; sentinel nodes; blood transfusion; Urology; kirurgi; särskilt urologi; Medicine; medicin;

    Abstract : Muscle-invasive urinary bladder cancer is a deadly disease. Mortality rates remained unchanged for decades despite radical surgery.After several randomized trials, we today know that cisplatin based chemotherapy given prior to cystectomy, improves survival for every tenth patient. READ MORE