Search for dissertations about: "thesis for chemotherapy"
Showing result 21 - 25 of 581 swedish dissertations containing the words thesis for chemotherapy.
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21. Anthracyclines : Toxicity and chemotherapy-induced mucositis
Abstract : Anthracyclines belong to a class of cytostatic compounds that are commonly used to treat various types of cancers, including lymphoma, breast cancer and primary liver cancer. The aim of this thesis was to study how two anthracyclines, doxorubicin and idarubicin, induced cytotoxicity in tumor cells, as well as their off-target effect on the gastrointestinal system. READ MORE
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22. Neurotoxic side effects and impact on daily life in patients with colorectal cancer with adjuvant oxaliplatin-based chemotherapy
Abstract : Introduction: Colorectal cancer (CRC) is one of the most common cancers globally. Chemotherapeutic drugs are frequently used in postoperative treatment. The platinum compound oxaliplatin (OXA) is an option for adjuvant treatment of patients with resected CRC, and has been shown to improve survival. OXA-induced neurotoxic side effects are common (e. READ MORE
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23. Immunopathogenesis of schistosomiasis mansoni : Immunity and pathology in a primary and a secondary infection following chemotherapy in the mouse and the baboo models
Abstract : This thesis describes a series of experiments aimed at elucidating the mechanisms ofimmunity and pathology elicited by both a primary infection and a reinfection exposure toSchistosoma mansoni following chemotherapy. The effects of a single large cercarial doseand a cumulatively equivalent dose, administered as multiple small doses are compared. READ MORE
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24. Pharmacogenetic biomarkers for chemotherapy-induced adverse drug reactions
Abstract : Cancer is a serious disease expected to be the world-leading cause of death in the 21st century. The use of harsh chemotherapies is motivated and accepted but, unfortunately, is often accompanied by severe toxicity and adverse drug reactions (ADRs). READ MORE
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25. Immunotherapy for pancreatic cancer
Abstract : Patients with pancreatic cancer have a short life expectancy, and only 20% of the patients diagnosed with pancreatic cancer can undergo surgery. Chemotherapy does not work well: Gemcitabine is the standard regimen with a 5-year survival rate of 1%–4% and a median survival time of 4-6 months; FOLFIRINOX chemotherapy regimen using four drugs was found to be more effective (median survival 11 months), but with substantial side effects. READ MORE