Search for dissertations about: "thesis for liver cancer"
Showing result 6 - 10 of 268 swedish dissertations containing the words thesis for liver cancer.
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6. Affibody-Based Molecular Imaging and Targeted Therapy of HER3-Expressing Cancer
Abstract : The human epidermal growth factor receptor type 3 (HER3) is overexpressed in different types of cancer and is a known contributor to disease progression and resistance to cancer therapy. This thesis is based on five original articles, which aimed to improve the diagnostic and therapeutic potential of affibody-based agents for management of HER3-expressing cancers. READ MORE
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7. Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas
Abstract : Contrast-enhanced magnetic resonance imaging (MRI) of the liver and pancreas is frequently performed to improve the sensitivity and specificity of lesion detection in these organs. The concept of using tissue-specific contrast media is to selectively enhance the normal parenchyma, but not lesions, so that the contrast between tumorous and normal tissue is increased, and lesion detectability improved. READ MORE
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8. Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy
Abstract : Metastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecular determinants of metastasis, breast cancer relapse and death rates remain unacceptably high. READ MORE
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9. Studies of tamoxifen resistance in breast cancer
Abstract : Oestrogen is one of the most important hormonal regulators and is known to play a key role in the development and growth of breast cancer. The majority of tumours have a hormone dependent growth, and this is indicated by the presence of oestrogen receptors (ERs). READ MORE
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10. Translational and clinical aspects of pancreatic cancer
Abstract : Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative treatment, surgery, is extensive with high morbidity and non-ignorable mortality. READ MORE