Search for dissertations about: "thesis in ANIMAL histology"
Showing result 1 - 5 of 46 swedish dissertations containing the words thesis in ANIMAL histology.
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1. Assessment of eosinophil degranulation in allergic diseases and experimental models
Abstract : In allergic disorders, the eosinophilic granulocytes migrate to affected tissues and release granule proteins with cytotoxic, immunoregulatory, and remodeling-promoting properties. Given that degranulation is reflected by a loss in eosinophil granule density of living cells, or by cell membrane rupture and release of intact granules, these morphological changes may represent a biomarker of the allergic disease. READ MORE
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2. Cross-modal Imaging in Lung Research: From µCT dosimetry to synchrotron phase contrast microtomography biomechanical insights in preclinical lung injury models
Abstract : Lung diseases continue to present a large burden to public health, especially in industrialized countries. For abetter understanding of the underlying patho-mechanisms in lung related diseases as well as for testing theefficacy of novel therapies, preclinical studies in animal models are indispensable. READ MORE
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3. The Polyamine Dependence of Cell Cycle Progression-Application in Breast Cancer Treatment
Abstract : In the normal functioning organism, there is a balance between cell proliferation, cell differentiation, and cell death. An imbalance in these processes results in different diseases. This thesis concerns the imbalance where there is too little cell death and cell differentiation with increased cell proliferation. READ MORE
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4. Development of techniques to determine extracellular matrix alterations in acute and chronic lung diseases and bioengineered tissues
Abstract : Acute and chronic lung diseases are a major cause of global mortality. While pharmacological approaches exist, no therapies are curative. The only option at end-stage disease is lung transplantation which is hampered by a chronic shortage of donor organs. READ MORE
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5. Analysis of effector pathways in arthritis
Abstract : Rheumatoid arthritis (RA) is a multifactorial, polygenic autoimmune disease. For effective treatment and control of RA, understanding of disease pathways and identification of genes involved are essential. Animal models are efficient tools to identify such pathogenic mechanisms and genes underlying the disease process. READ MORE