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Showing result 1 - 5 of 88 swedish dissertations matching the above criteria.

2. 1. The Role of Chlamydia pneumoniae-induced Platelet Activation in Cardiovascular Disease : In vitro and In vivo studies

   Author : Hanna Kälvegren; Torbjörn Bengtsson; Arina Richter; Erik Kihlström; Kenneth Persson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia pneumoniae; Platelet; atherosclerosis; Infection; LDL-oxidation; Percutaneous coronary intervention; Cardiovascular disease; Serotonin; Reactive oxygen species production; Pharmacology; Farmakologi;

   Abstract : The common risk factors for atherosclerosis, such as obesity, high cholesterol levels, sedentary lifestyle, diabetes and high alcohol intake, only explain approximately 50% of cardiovascular disease events. It is thereby important to identify new mechanisms that can stimulate the process of atherosclerosis. READ MORE

4. 2. Thrombosis in Children

   Author : Olof Rask; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Child; Estradiol; Heart Defects; Congenital; Hemostasis; Protein C Inhibitor; Risk factors; Thrombophilia; Thromboembolism; Autoantibodies; Adolescent;

   Abstract : Aims: The general objective was to further elucidate thromboembolic disease in children and thereby help improve the care of these patients. More specific aims were as follows: to determine what children are affected by thrombosis; to discern any gender or age differences related to thrombosis; to identify prothrombotic risk factors; to ascertain whether autoantibodies against coagulation proteins constitute a risk factor for childhood thrombosis; to study girls receiving estrogen treatment with regard to induced hemostatic changes and efficacy of the therapy; to investigate long-term effects on the hemostatic system in children subjected to heart surgery. READ MORE

5. 3. Clinical and experimental insights into the use of mechanical chest compressions during prolonged resuscitation in the coronary catheterization laboratory

   Author : Henrik Wagner; Kardiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac arrest; mechanical chest compressions; PCI; survival; coronary artery blood flow; epinephrine;

   Abstract : INTRODUCTION. Prolonged cardiopulmonary resuscitation (CPR) with manual chest compressions (CC) during simultaneous percutaneous coronary intervention (PCI) is exceedingly difficult, with high mortality rates. The use of a mechanical CC (MCC) device can overcome the ordeal of manual CC. READ MORE

6. 4. Impact of chronic total occlusions, arterial access site, and pretreatment with antiplatelet drugs on mortality in patients with ischemic heart disease: A report from the SWEDEHEART registry

   Author : Christian Dworeck; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute coronary syndrome; acute myocardial infarction; coronary artery disease; mortality; chronic total occlusion; pretreatment; antiplatelet; P2Y12; radial access; PCI; SWEDEHEART; SCAAR; RIKS-HIA; cardiology;

   Abstract : Impact of chronic total occlusions, arterial access site and pretreatment with antiplatelet drugs on mortality in patients with ischemic heart disease: A report from the SWEDEHEART registry Background Treatment of ischemic heart disease has advanced substantially in the past half-century. However, despite these achievements the survival rates in high-income countries such as Sweden have reached a plateau in the last decade. READ MORE

7. 5. Invasive treatment of coronary artery disease : Aspects on antithrombotic and percutaneous treatment options

   Author : Per Grimfjärd; Stefan James; Christoph Varenhorst; P Hedberg; Lene Holmvang; Uppsala universitet; []
   Keywords : PCI; STEMI; stent thrombosis; bivalirudin; heparin; bioresorbable scaffold; cangrelor; drug eluting stent; DES; Cardiology; Kardiologi;

   Abstract : The outcome after percutaneous coronary intervention (PCI) has improved considerably thanks to more effective antithrombotic treatment strategies and improved coronary stents. Stent thrombosis (ST) is a rare complication to PCI associated with considerable mortality and morbidity. READ MORE