Search for dissertations about: "thesis in bacteria genome"

Showing result 1 - 5 of 171 swedish dissertations containing the words thesis in bacteria genome.

  2. 1. Dynamics of the Bacterial Genome : Rates and Mechanisms of Mutation

    Author : Sanna Koskiniemi; Dan Andersson; Diarmaid Hughes; Ivan Matic; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria; bacterial evolution; genome reduction; gene loss; serial passage; DNA homology; tranlesion DNA polymerase; stress; Microbiology; Mikrobiologi; Bacteriology; Bakteriologi; Evolutionary Genetics; Evolutionär genetik; Mikrobiologi; Microbiology;

    Abstract : Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. READ MORE

  4. 2. Dynamics and Mechanisms of Adaptive Evolution in Bacteria

    Author : Song Sun; Dan Andersson; Diarmaid Hughes; Josep Casadesús; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; adaptive evolution; mutation; genome rearrangements; antibiotic resistance; gene amplification; genome reduction; directed evolution; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Determining the properties of mutations is fundamental to understanding the mechanisms of adaptive evolution. The major goal of this thesis is to investigate the mechanisms of bacterial adaptation to new environments using experimental evolution. READ MORE

  5. 3. Studies of Genome Diversity in Bartonella Populations : A journey through cats, mice, men and lice

    Author : Hillevi Lina Lindroos; Siv G. E. Andersson; Richard Birtles; Uppsala universitet; []
    Keywords : Biology; Bartonella; genome content; genome rearrangement; gene expression; phage; microarray; PFGE; MLST; Biologi;

    Abstract : Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. READ MORE

  6. 4. Genome Evolution and Host Adaptation in Bartonella

    Author : Eva Caroline Berglund; Siv GE Andersson; Brendan Wren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bartonella; genome evolution; genome diversity; phage; gene transfer agent; secretion system; microarray; Bioinformatics; Bioinformatik; Evolutionary Genetics; evolutionär genetik;

    Abstract : Bacteria of the genus Bartonella infect the red blood cells of a wide range of wild and domestic mammals and are transmitted between hosts by blood-sucking insects. Although most Bartonella infections are asymptomatic, the genus contains several human pathogens. READ MORE

  7. 5. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species

    Author : Anna Carolin Frank; Siv Andersson; Stewart Cole; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; Biology; Biologi;

    Abstract : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. READ MORE